Recombinant Mouse CSF1R protein(Met1-Ser511), His-tagged
Cat.No. : | Csf1r-337M |
Product Overview : | Recombinant Mouse CSF1R (NP_001032948.2) (Met 1-Ser 511) was expressed in HEK293, fused with a polyhistidine tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
- Download
Source : | HEK293 |
Species : | Mouse |
Tag : | C-His |
Protein length : | Met1-Ser511 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | Immobilized M-CSF Protein, Mouse, Recombinant (ECD) at 2 μg/mL (100 μL/well) can bind CSF1R Protein, Mouse, Recombinant (His Tag), the EC50 is 180-640 ng/mL. |
Molecular Mass : | The secreted recombinant mouse CSF1R consists of 503 amino acids and has a predicted molecular mass of 56.8 kDa. As a result of glycosylation, the apparent molecular mass of rm CSF1R is approximately 80-90 kDa in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 97 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Csf1r colony stimulating factor 1 receptor [ Mus musculus ] |
Official Symbol : | CSF1R |
Synonyms : | CSF1R; colony stimulating factor 1 receptor; macrophage colony-stimulating factor 1 receptor; c-fms; CSF-1-R; CSF-1 receptor; proto-oncogene fms; proto-oncogene c-Fms; Fms; CD115; Csfmr; Fim-2; CSF-1R; M-CSFR; M-CSF-R; AI323359; |
Gene ID : | 12978 |
mRNA Refseq : | NM_001037859 |
Protein Refseq : | NP_001032948 |
Products Types
◆ Recombinant Protein | ||
CSF1R-067H | Recombinant Human CSF1R Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
CSF1R-373H | Recombinant Human CSF1R Protein, His-tagged | +Inquiry |
CSF1R-374H | Recombinant Human CSF1R Protein, Fc-tagged | +Inquiry |
CSF1R-020H | Recombinant Human CSF1R Protein, C-His-tagged | +Inquiry |
CSF1R-979R | Recombinant Rhesus CSF1R Protein (Met1-Glu512) (Cys378Arg), HlgG1 Fc-tagged | +Inquiry |
◆ Lysates | ||
CSF1R-823RCL | Recombinant Rat CSF1R cell lysate | +Inquiry |
CSF1R-2739HCL | Recombinant Human CSF1R cell lysate | +Inquiry |
CSF1R-2091MCL | Recombinant Mouse CSF1R cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1574 | CSF1R Kinase Binding Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, drugs like pexidartinib have been approved for the treatment of certain rare tumors called tenosynovial giant cell tumors (TGCT) that overexpress CSF1R.
CSF1R inhibitors can modulate the tumor microenvironment by reducing the number of tumor-associated macrophages and promoting an anti-tumor immune response.
Yes, CSF1R inhibitors are often used in combination with chemotherapy and immunotherapy to enhance treatment effectiveness.
CSF1R inhibitors are being investigated for cancer therapy to block tumor-promoting macrophages and slow down cancer progression.
Research is ongoing, and CSF1R inhibitors are being explored as a potential therapy for neurodegenerative diseases, but no FDA-approved treatments currently exist.
Customer Reviews (3)
Write a reviewWith its remarkable quality, reliability, and the manufacturer's excellent technical support, I am confident that it will be an invaluable asset in driving my scientific inquiries forward and facilitating groundbreaking discoveries in my field.
This variety allows me to select the most appropriate option based on the specific requirements of my research.
the manufacturer's commitment to quality control and rigorous testing guarantees the reliability and reproducibility of the CSF1R protein, which is essential for obtaining accurate and consistent results.
Ask a Question for All CSF1R Products
Required fields are marked with *
My Review for All CSF1R Products
Required fields are marked with *
Inquiry Basket