Active Recombinant Mouse Cxcl5 Protein (74 aa)
Cat.No. : | Cxcl5-228C |
Product Overview : | Recombinant mouse LIX/CXCL5 (74aa) produced in CHO cells is a single polypeptide chain containing 74 amino acids. rmLIX/CXCL5(74aa) has a molecular mass of 8 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Description : | Mouse LIX (C-X-C motif chemokine 5) is a small cytokine belonging to the CXC chemokine family that is cleaved into the following 2 chains [GCP-2(1-78) and GCP-2(9-78)]. Mouse LIX plays a role in reducing sensitivity to sunburn pain in some subjects, and is a potential target which could be used to understand more about pain in other inflammatory conditions. It is most closely related to two highly homologous human neutrophil chemoattractants GCP-2 and ENA-78. The first 78 amino acid residues within the predicted mature mouse LIX shares approximately 61% and 55% amino acid identity with human GCP-2 and ENA-78. This chemokine stimulates the chemotaxis of neutrophils possessing angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2. |
Source : | CHO |
Species : | Mouse |
Form : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Bio-activity : | The EC50 value of mouse LIX/CXCL5 (74aa) on Ca^2+ mobilization assay in CHO-K1/Gα15/mCXCR2 cells (human Gα15 and mouse CXCR2 stably expressed in CHO-K1 cells) is less than 200 ng/mL. |
Molecular Mass : | 8 kDa, observed by reducing SDS-PAGE. |
Protein Length : | 74 |
AA Sequence : | VIAATELRCVCLTVTPKINPKLIAN LEVIPAGPQCPTVEVIAKLKNQKEV CLDPEAPVIKKIIQKILGSDKKKA |
Endotoxin : | < 0.2 EU/μg, determined by LAL method. |
Purity : | > 98% as analyzed by SDS-PAGE. |
Storage : | Lyophilized recombinant mouse LIX/CXCL5 remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution,mouse LIX/CXCL5 should be stable up to 1 week at 4 centigrade or up to 2 months at -20 centigrade. |
Storage Buffer : | Lyophilized after extensive dialysis against PBS. |
Reconstitution : | Reconstituted in ddH2O or PBS at 100 μg/mL. |
Gene Name : | Cxcl5 chemokine (C-X-C motif) ligand 5 [ Mus musculus ] |
Official Symbol : | Cxcl5 |
Synonyms : | CXCL5; chemokine (C-X-C motif) ligand 5; C-X-C motif chemokine 5; cytokine LIX; small-inducible cytokine B5; granulocyte chemotactic protein-2; small inducible cytokine B subfamily, member 5; small inducible cytokine subfamily B, member 15; LIX; GCP-2; Scyb5; Scyb6; ENA-78; AMCF-II; |
Gene ID : | 20311 |
mRNA Refseq : | NM_009141 |
Protein Refseq : | NP_033167 |
UniProt ID : | P50228 |
Products Types
◆ Recombinant Protein | ||
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CXCL5-424C | Active Recombinant Human CXCL5 Protein (9-78, 70 aa) | +Inquiry |
CXCL5-272H | Active Recombinant Human CXCL5 Protein (Arg45-Asn114), N-His tagged, Animal-free, Carrier-free | +Inquiry |
CXCL5-692H | Recombinant Human CXCL5 Protein, His (Fc)-Avi-tagged | +Inquiry |
Cxcl5-2398M | Active Recombinant Mouse Cxcl5 Protein | +Inquiry |
◆ Lysates | ||
CXCL5-7167HCL | Recombinant Human CXCL5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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