| Description : |
Fibroblast Growth Factor-9 (FGF-9), also known as Glia-activating factor (GAF) and HBGF-9, belongs to the heparin-binding growth factors family. It is a secreted protein that exists as monomer or homodimer. It interacts with FGFR-1, FGFR-2, FGFR-3, and FGFR-4 and plays an important role in regulating cell proliferation, differentiation and migration. It is reported that FGF-9 may be involved in glial cell growth and differentiation during development, gliosis during brain tissue regeneration, and glial tumor growth stimulation. Other reports indicate that FGF-9 plays a role in male development. |
| Source : |
CHO |
| Species : |
Mouse |
| Form : |
Sterile Filtered White lyophilized (freeze-dried) powder. |
| Bio-activity : |
ED50 < 2 ng/mL, measured in a cell proliferation assay using 3T3 cells. |
| Molecular Mass : |
~28 kDa, observed by reducing SDS-PAGE. |
| AA Sequence : |
LGEVGNYFGVQDAVPFGNVPVLPVD SPVLLSDHLGQSEAGGLPRGPAVTD LDHLKGILRRRQLYCRTGFHLEIFP NGTIQGTRKDHSRFGILEFISIAVG LVSIRGVDSGLYLGMNEKGELYGSE KLTQECVFREQFEENWYNTYSSNLY KHVDTGRRYYVALNKDGTPREGTRT KRHQKFTHFLPRPVDPDKVPELYKD ILSQS |
| Endotoxin : |
< 0.2 EU/μg, determined by LAL method. |
| Purity : |
> 95% as analyzed by SDS-PAGE and HPLC. |
| Storage : |
Lyophilized recombinant Murine Fibroblast Growth Factor-9 remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, Murine Fibroblast Growth Factor-9should be stable up to 1 week at 4 centigrade or up to 2 months at -20 centigrade. |
| Storage Buffer : |
Lyophilized after extensive dialysis against PBS. |
| Reconstitution : |
Reconstituted in ddH2O or PBS at 100 μg/mL. |
