Recombinant Mouse Foxl2 Protein, Myc/DDK-tagged
Cat.No. : | Foxl2-3075M |
Product Overview : | Purified recombinant protein of mouse full-length forkhead box L2 (Foxl2), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9. Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2. Is a regulator of CYP19 expression. Is a transcriptional repressor of STAR. Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 39.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Foxl2 forkhead box L2 [ Mus musculus (house mouse) ] |
Official Symbol : | Foxl2 |
Synonyms : | FOXL2; forkhead box L2; forkhead box protein L2; P-Frk; pituitary forkhead factor; putative transcription factor foxl2; BPES; Pfrk; PINTO; AU045128 |
Gene ID : | 26927 |
mRNA Refseq : | NM_012020 |
Protein Refseq : | NP_036150 |
UniProt ID : | O88470 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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