Recombinant Mouse Smpdl3b Protein, MYC/DDK-tagged Smpdl3b-159M

Recombinant Mouse Smpdl3b Protein, MYC/DDK-tagged


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Recombinant Mouse Smpdl3b Protein, MYC/DDK-tagged

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Cat.No. : Smpdl3b-159M
Product Overview : Purified recombinant protein of full-length mouse sphingomyelin phosphodiesterase, acid-like 3B (Smpdl3b), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : Lipid-modulating phosphodiesterase. Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll-like receptor signaling. Has in vitro phosphodiesterase activity, but the physiological substrate is unknown. Lacks activity with phosphocholine-containing lipids, but can cleave CDP-choline, and can release phosphate from ATP and ADP (in vitro).
Source : HEK293T
Species : Mouse
Molecular Mass : 51.6 kDa
Purity : >80%, as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Smpdl3b sphingomyelin phosphodiesterase, acid-like 3B [ Mus musculus (house mouse) ]
Official Symbol : Smpdl3b
Synonyms : Smpdl3b; sphingomyelin phosphodiesterase, acid-like 3B; Asml3b; AU045240; 1110054A24Rik; acid sphingomyelinase-like phosphodiesterase 3b; ASM-like phosphodiesterase 3b
Gene ID : 100340
mRNA Refseq : NM_133888
Protein Refseq : NP_598649
UniProt ID : P58242

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