Recombinant Mouse Tnfrsf10b Protein, Myc/DDK-tagged
Cat.No. : | Tnfrsf10b-6544M |
Product Overview : | Purified recombinant protein of mouse full-length tumor necrosis factor receptor superfamily, member 10b (Tnfrsf10b), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 42.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b [ Mus musculus (house mouse) ] |
Official Symbol : | Tnfrsf10b |
Synonyms : | TNFRSF10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor superfamily member 10B; death receptor 5; KILLER/DR5 TRAIL death-inducing receptor; MK; DR5; Ly98; KILLER; TRICKB; TRAILR2; TRICK2A; TRICK2B |
Gene ID : | 21933 |
mRNA Refseq : | NM_020275 |
Protein Refseq : | NP_064671 |
UniProt ID : | Q9QZM4 |
Products Types
◆ Recombinant Protein | ||
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TNFRSF10B-599H | Active Recombinant Human TNFRSF10B Protein, His-Avi-tagged, Biotinylated | +Inquiry |
TNFRSF10B-15H | Active Recombinant Human TNFRSF10B Protein | +Inquiry |
◆ Lysates | ||
TNFRSF10B-2829HCL | Recombinant Human TNFRSF10B cell lysate | +Inquiry |
TNFRSF10B-2397MCL | Recombinant Mouse TNFRSF10B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionActivation of TNFRSF10B triggers apoptotic pathways, leading to programmed cell death in cancer cells.
TNFRSF10B has been implicated in certain autoimmune diseases and neurodegenerative disorders, highlighting its diverse roles in various physiological processes.
TNFRSF10B expression levels may serve as a potential diagnostic marker for certain cancers, aiding in cancer detection and prognosis.
TNFRSF10B expression is often altered in various cancers, including breast cancer, colorectal cancer, and lung cancer.
Side effects may occur, and ongoing research aims to minimize these effects while maximizing the therapeutic benefits of targeting TNFRSF10B.
Customer Reviews (3)
Write a reviewThe combination of high-quality TNFRSF10B protein and excellent technical support provided by the manufacturer makes them the ideal choice for my research.
The manufacturer's extensive experience and expertise in the field of TNFRSF10B protein research make them a trusted partner.
The manufacturer's commitment to providing excellent technical support is highly valuable.
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