Species : |
Mouse |
Source : |
Mammalian Cells |
Tag : |
Non |
Description : |
The CD30 ligand is a type II transmembrane glycoprotein of the tumor necrosis factor ligand superfamily. CD30L is expressed on the cell surface of activated T cells, B cells, and monocytes. Recombinant CD30L has been shown to co-stimulate T cells and to act as a mitogen for Hodgkin"s disease derived cell lines. The receptor for CD30L, CD30/ TNFRSF8/CD153, is a type I cytokine receptor that is highly expressed by activated T cells, Hodgkin and Reed- Sternberg (H-RS) cells, and anaplastic large cell lymphoma cells. CD30 ligation by CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation and cell death by apoptosis. |
Molecular Weight : |
The predicted molecular weight of Recombinant Mouse CD30L is Mr 22 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 30-45 kDa. |
State Of Matter : |
Lyophilized. |
Purity : |
>95% by SDS Page and analyzed by silver stain. |
Endotoxin : |
<0.1 ng per 1 µg as determined by the LAL method. |
Storage And Stability : |
This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |