Recombinant Pseudomonas Aeruginosa LASA Protein (237-418 aa), His-SUMO-tagged
| Cat.No. : | LASA-2104P |
| Product Overview : | Recombinant Pseudomonas Aeruginosa (strain ATCC 15692/PAO1/1C/PRS 101/LMG 12228) LASA Protein (237-418 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Protein Description: Full Length of Mature Protein. |
- Specification
- Gene Information
- Related Products
| Description : | Involved in proteolysis and elastolysis (degradation of the host protein elastin). Has staphylolytic activity (degrades pentaglycine cross-links in cell wall peptidogylcan), preferring Gly-Gly-|-X substrates where X is Ala or Gly (PubMed:11179971). Enhances the elastolytic but not proteolytic activity of elastase (lasB) and elastolytic activity of other proteases (PubMed:2110137). Degradation of host elastin is likely to contribute to the pathogenicity of P.aeruginosa. While either His-317 or His-356 can abstract a proton in the hydrolysis reaction, the same residue performs both functions in a given catalytic cycle, with the other stabilizing the catalytic intermediate. |
| Source : | E. coli |
| Species : | Pseudomonas Aeruginosa |
| Tag : | His-SUMO |
| Form : | Tris-based buffer,50% glycerol |
| Molecular Mass : | 36.0 kDa |
| Protein length : | 237-418 aa |
| AA Sequence : | APPSNLMQLPWRQGYSWQPNGAHSN TGSGYPYSSFDASYDWPRWGSATYS VVAAHAGTVRVLSRCQVRVTHPSGW ATNYYHMDQIQVSNGQQVSADTKLG VYAGNINTALCEGGSSTGPHLHFSL LYNGAFVSLQGASFGPYRINVGTSN YDNDCRRYYFYNQSAGTTHCAFRPL YNPGLAL |
| Purity : | > 90% as determined by SDS-PAGE. |
| Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
| Gene Name : | lasA protease LasA [ Pseudomonas aeruginosa PAO1 ] |
| Official Symbol : | LASA |
| Synonyms : | lasA; Staphylolytic protease; |
| Gene ID : | 878260 |
| Protein Refseq : | NP_250562 |
| UniProt ID : | P14789 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket
