"Lag3" Related Products


Recombinant Rat Lag3 protein, His-tagged

Cat.No.: Lag3-1832R
Product Overview: Recombinant Rat LAG3 /CD223 Protein (Rat LAG3 / CD223) Gly 24 - Leu 442 (Accession # NP_997678) was produced in human 293 cells (HEK293).
Description: Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.
Source: HEK293
Species: Rat
Tag : His
Predicted N Terminal: Gly 24
Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.
Molecular Mass: Rat LAG3 / CD223 is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 47.6 kDa. DTT-reduced Protein migrates as 55 kDa in SDS-PAGE due to glycosylation.
Protein length: AA Gly 24 - Leu 442
Endotoxin: Less than 1.0 EU per μg of the Rat LAG3 / CD223 by the LAL method.
Purity: >90% as determined by SDS-PAGE.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C).
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name: Lag3 lymphocyte activating 3 [ Rattus norvegicus (Norway rat) ]
Official Symbol: Lag3
Synonyms: CD223; lymphocyte-activation gene 3
Gene ID: 297596
mRNA Refseq: NM_212513.2
Protein Refseq: NP_997678.2
UniProt ID: Q5BK54

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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