| Species : |
Rat |
| Source : |
HEK293 |
| Tag : |
His |
| Protein Length : |
AA Gly 24 - Leu 442 |
| Description : |
Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens. |
| Predicted N Terminal : |
Gly 24 |
| Form : |
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
| Molecular Mass : |
Rat LAG3 / CD223 is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 47.6 kDa. DTT-reduced Protein migrates as 55 kDa in SDS-PAGE due to glycosylation. |
| Endotoxin : |
Less than 1.0 EU per μg of the Rat LAG3 / CD223 by the LAL method. |
| Purity : |
>90% as determined by SDS-PAGE. |
| Storage : |
Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C). |
| Reconstitution : |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
