Cat.No. : |
il4-22Z |
Product Overview : |
Recombinant Zebrafish il4 was expressed in Yeast. |
Description : |
Interleukin-4 (IL-4) induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4. IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. IL-4 induces B-cell class switching to IgE, and up-regulates MHC class II production. Overproduction of IL-4 is associated with allergies. |
Source : |
Yeast |
Species : |
Zebrafish |
Form : |
Lyophilized without carrier protein. |
Molecular Mass : |
12.4 kDa (calculated) |
AA Sequence : |
SKLKIDEILL MEIIQSVNGI LNGKGEKMDL DQFIPDIYET GHYSKKTLCQ AGMALKGKIP SRSHLQRQLN AYAAYTGTGN CSVSTSGECT MKEFLEKTKA CCHYLYSAQR T (111) |
Purity : |
>95% as visualized by SDS-PAGE analysis. |
Applications : |
The zebrafish IL-4 protein can be used in cell culture, as an IL-4 ELISA Standard, and as a Western Blot Control. |
Storage : |
Stable for up to twelve months from date of receipt at -20 centigrade. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20 centigrade. Avoid repeated freeze/thaw cycles. |
Reconstitution : |
Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. |