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ABCC6

  • Official Full Name

    ATP-binding cassette, sub-family C (CFTR/MRP), member 6

  • Overview

    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene.
  • Synonyms

    ABCC6; ATP-binding cassette, sub-family C (CFTR/MRP), member 6; ARA, pseudoxanthoma elasticum , PXE; URG7 protein; multidrug resistance-associated protein 6; EST349056; MLP1; MRP6; URG7; MOAT-E; ATP-binding cassette sub-family C member 6; multi-specific organic anion transporter E; anthracycline resistance-associated protein; ARA; PXE; PXE1; ABC34; GACI2; MOATE;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ABCC6-9219H Recombinant Human ABCC, His-tagged E.coli His 1219-1503a.a.
Human ABCC6-052H Recombinant Human ABCC6 Protein, GST-Tagged Wheat Germ GST
Human ABCC6-051H Recombinant Human ABCC6 Protein, GST-Tagged Wheat Germ GST
Human ABCC6-632H Recombinant Human ABCC6 Mammalian Cell His
Human ABCC6-6HCL Recombinant Human ABCC6 cell lysate N/A
Human ABCC6-2403H-B Recombinant Human ABCC6 Protein Pre-coupled Magnetic Beads HEK293
Human ABCC6-633H Recombinant Human ABCC6 Protein, His-tagged E.coli His
Human ABCC6-2403H Recombinant Human ABCC6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Abcc6-8120M Recombinant Mouse Abcc6 protein, His & T7-tagged E.coli His/T7 Ile1260~Ala1498 (Accession # Q9R1S7)
Mouse ABCC6-1104M Recombinant Mouse ABCC6 Protein Mammalian Cell His
Mouse ABCC6-200M-B Recombinant Mouse ABCC6 Protein Pre-coupled Magnetic Beads HEK293
Mouse ABCC6-200M Recombinant Mouse ABCC6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ABCC6-407R Recombinant Rat ABCC6 Protein Mammalian Cell His
Rat Abcc6-8121R Recombinant Rat Abcc6 protein, His & T7-tagged E.coli His/T7 Cys1260~Ala1502 (Accession # O88269)
Rat ABCC6-62R Recombinant Rat ABCC6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ABCC6-62R-B Recombinant Rat ABCC6 Protein Pre-coupled Magnetic Beads HEK293
Chicken ABCC6-4541C Recombinant Chicken ABCC6 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ABCC6 Related Articles

ABCC6 involved in several pathways and played different roles in them. We selected most pathways ABCC6 participated on our site, such as ABC transporters, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCC6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ABC transportersABCC8;ABCD3;ABCA5;ABCB7;ABCB3L1;ABCA6;ABCC9;ABCB6;ABCA8

ABCC6 has several biochemical functions, for example, ATP binding, ATPase activity, coupled to transmembrane movement of substances, transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCC6 itself. We selected most functions ABCC6 had, and list some proteins which have the same functions with ABCC6. You can find most of the proteins on our site.

Function Related Protein
ATP bindingP2RY1;AKT3;DQX1;RUNX3;JAK3;UBA7;MADD;PRKD2;ERN1
ATPase activity, coupled to transmembrane movement of substancesTAP1;ABCD3A;ABCD4;ABCB10;ABCC1;ABCB6A;ABCC9;ABCB5;ABCG8
transporter activityCDH17;SLC12A2;LCN9;ATP6V1C1;SEC14L3;ABCC1;SLC15A2;OSTA;SLC13A1

ABCC6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCC6 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCC6.

A1BG; FURIN; NR4A1; AK2; CRYL1

Kirsch, AH; Smaczny, N; et al. Regulatory T Cells Improve Nephrocalcinosis but Not Dystrophic Cardiac Calcinosis in DBA/2 Mice. AMERICAN JOURNAL OF PATHOLOGY 183:382-390(2013).
Pomozi, V; Le Saux, O; et al. ABCC6 Is a Basolateral Plasma Membrane Protein. CIRCULATION RESEARCH 112:E148-+(2013).
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