Recombinant Human ABCC6 Protein, His-tagged

• Cat.No.: ABCC6-633H
• Product Overview: Purified recombinant protein of Human ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (ABCC6), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: 10.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 50mM Tris, pH8.0.8M Urea.

Gene Information

• Gene Name: ABCC6 ATP binding cassette subfamily C member 6 [ Homo sapiens (human) ]
• Official Symbol: ABCC6
• Synonyms: ABCC6; ATP binding cassette subfamily C member 6; ARA; PXE; MLP1; MRP6; PXE1; URG7; ABC34; GACI2; MOATE; MOAT-E; EST349056; multidrug resistance-associated protein 6; URG7 protein; ATP-binding cassette, sub-family C (CFTR/MRP), member 6; anthracycline resistance-associated protein; multi-specific organic anion transporter E
• Gene ID: 368
• mRNA Refseq: NM_001079528
• Protein Refseq: NP_001072996
• MIM: 603234
• UniProt ID: O95255