amhr2
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  • Official Full Name
  • anti-Mullerian hormone receptor, type II
  • Background
  • This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.
  • Synonyms
  • AMHR2; anti-Mullerian hormone receptor, type II; anti-Muellerian hormone type-2 receptor; MISR2; MISRII; M?llerian inhibiting substance type II receptor; AMH type II receptor; AMHR2_HUMAN; Anti-Muellerian hormone type II receptor; MGC141312; MIS type II receptor; MRII; Muellerian hormone type 2 receptor; Muellerian hormone type II receptor; Mullerian hormone receptor type II; OTTHUMP00000242707; OTTHUMP00000242708; OTTHUMP00000242709; Mullerian inhibiting substance type II receptor; AMHR
Cat.#:AMHR2-521HTag:N/A
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human AMHR2 protein
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Cat.#:AMHR2-535HTag:Fc
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human AMHR2, Fc-tagged, Biotinylated
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Cat.#:AMHR2-536HTag:Fc
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human AMHR2, Fc-tagged
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Cat.#:AMHR2-5601HTag:Fc
Source (Host):NS0Species:Human
Product nameRecombinant Human Anti-Mullerian Hormone Receptor, Type II, Fc-tagged
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Cat.#:AMHR2-1598MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse AMHR2 Protein
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Cat.#:AMHR2-651RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat AMHR2 Protein
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Cat.#:AMHR2-8883HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human AMHR2 293 Cell Lysate
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Involved Pathway

AMHR2 involved in several pathways and played different roles in them. We selected most pathways AMHR2 participated on our site, such as Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with AMHR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
TNFSF4; INHBE; GM13305; BMP2; IL4R; GM2506; IFNW1; CNTFR; IL18; KDRL
TGF-beta signaling pathway
ACVR2A; BMP4; BMPR2A; BMP8B; GDF6; SMAD5; ACVR1BA; LTBP1; EP300; CUL1B

Protein Function

AMHR2 has several biochemical functions, for example, ATP binding, anti-Mullerian hormone receptor activity, hormone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AMHR2 itself. We selected most functions AMHR2 had, and list some proteins which have the same functions with AMHR2. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein PFKMA; DGKQ; CHD4; HSP70; ATAD5; PAK6; EPHA3; ACTR1A; UBE2L3; MYHZ1.2
Function anti-Mullerian hormone receptor activity
Related Protein AMHR2
Function hormone binding
Related Protein LRP2; ADIPOR1B; UCN2; NPR2; CALR; MC1R; NPR3; MTNR1A; AMHR2; ADIPOR1A
Function metal ion binding
Related Protein USP19; SP8B; CYP2AA4; ZNF684; ZFYVE16; ESYT1; CYB5D1; RNF220A; EXT1; RAF1A
Function protein binding
Related Protein CSRNP1; PITPNC1; ZBTB24; CDC6; PARD6A; DNTT; BLOC1S5; NEIL2; E4F1; Ar
Function receptor activity
Related Protein ADIPOR1B; KLRB1F; GRIK5; CD5; NPY2R; ITGB1B.1; ITGB3B; LILRB4; EXTL3; CD200R3
Function receptor signaling protein serine/threonine kinase activity
Related Protein BMPR2; STK24A; STK25A; SBK3; TGFBR1B; ACVR1L; PAK2B; ACVR1C; PANK1A; ACVR1BA
Function transforming growth factor beta receptor activity, type II
Related Protein TGFBR2; AMHR2

Interacting Protein

AMHR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMHR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of AMHR2.
HSP90AB1; HSP90AA1; CDC37; Hacd3