| Description : |
This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2009] |
| Source : |
Wheat Germ |
| Species : |
Human |
| Form : |
Liquid |
| Molecular Mass : |
63.1 kDa |
| AA Sequence : |
MLGSLGLWALLPTAVEAPPNRRTCV FFEAPGVRGSTKTLGELLDTGTELP RAIRCLYSRCCFGIWNLTQDRAQVE MQGCRDSDEPGCESLHCDPSPRAHP SPGSTLFTCSCGTDFCNANYSHLPP PGSPGTPGSQGPQAAPGESIWMALV LLGLFLLLLLLLGSIILALLQRKNY RVRGEPVPEPRPDSGRDWSVELQEL PELCFSQVIREGGHAVVWAGQLQGK LVAIKAFPPRSVAQFQAERALYELP GLQHDHIVRFITASRGGPGRLLSGP LLVLELHPKGSLCHYLTQYTSDWGS SLRMALSLAQGLAFLHEERWQNGQY KPGIAHRDLSSQNVLIREDGSCAIG DLGLALVLPGLTQPPAWTPTQPQGP AAIMEAGTQRYMAPELLDKTLDLQD WGMALRRADIYSLALLLWEILSRCP DLRPDSSPPPFQLAYEAELGNTPTS DELWALAVQERRRPYIPSTWRCFAT DPDGLRELLEDCWDADPEARLTAEC VQQRLAALAHPQESHPFPESCPRGC PPLCPEDCTSIPAPTILPCRPQRSA CHFSVQQGPCSRNPQPACTLSPV |
| Applications : |
Antibody Production; Functional Study; Compound Screening |
| Usage : |
Heating may cause protein aggregation. Please do not heat this product before electrophoresis. |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
