ARHGAP22 Protein, Rho GTPase activating protein 22

ARHGAP22

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ARHGAP22

Official Full Name Rho GTPase activating protein 22
Background This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS;superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt;and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of;these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been;found for this gene.
Synonyms ARHGAP22; Rho GTPase activating protein 22; rho GTPase-activating protein 22; RhoGAP2; Rho GTPase activating protein 2; rho-type GTPase-activating protein 22; RhoGap22
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ARHGAP22-2578H Recombinant Human ARHGAP22 Protein, His-tagged E.coli His
    Human ARHGAP22-2588H Recombinant Human ARHGAP22 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human ARHGAP22-764H Recombinant Human ARHGAP22 protein, GST-tagged Wheat Germ GST
    Mouse ARHGAP22-1861M Recombinant Mouse ARHGAP22 Protein Mammalian Cell His

    ARHGAP22 involved in several pathways and played different roles in them. We selected most pathways ARHGAP22 participated on our site, such as Rho GTPase cycle, Signal Transduction, Signaling by Rho GTPases, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGAP22 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Rho GTPase cycle FGD4; ARHGAP17B; FGD4A; TAGAP; DEPDC7; RHOT1A; CHN1; ARHGAP26; RHOV; ARHGAP24
    Signal Transduction APLNR; RARGA; NF2A; ARHGAP9; RHOT1B; NMBB; PDK2; MKS1; LGR5; BCL9L
    Signaling by Rho GTPases CHN1; TAGAPA; ABI1A; TAGAP; RHOT1; NOXO1; OPHN1; ARHGAP9; ARHGAP17A; ARHGAP18

    ARHGAP22 has several biochemical functions, for example, GTPase activator activity, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGAP22 itself. We selected most functions ARHGAP22 had, and list some proteins which have the same functions with ARHGAP22. You can find most of the proteins on our site.

    Function Related Protein
    GTPase activator activity ARHGAP22; BNIP2; TBC1D24; RANGAP1; TBC1D30; ARHGAP1; ARHGAP24; AGFG1B; ARHGAP29B; GRTP1A
    molecular_function CEP89; IER3IP1; GM996; PRL8A8; TMEM198; TMEM119B; TNNI2A.3; CRYGM2D4; CMIP; GM614

    ARHGAP22 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGAP22 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGAP22.

    PRKAA1

    Bosch, DE; Siderovski, DP; et al. G protein signaling in the parasite Entamoeba histolytica. EXPERIMENTAL AND MOLECULAR MEDICINE 45:-(2013).
    Qian, XL; Durkin, ME; et al. Inactivation of the Dlc1 Gene Cooperates with Downregulation of p15(INK4b) and p16(Ink4a), Leading to Neoplastic Transformation and Poor Prognosis in Human Cancer. CANCER RESEARCH 72:5900-5911(2012).

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