Recombinant Human ARHGAP22 Protein, His-tagged

• Cat.No.: ARHGAP22-2578H
• Product Overview: Recombinant Human ARHGAP22 protein, fused to His-tagged at N-terminus, was expressed in E. coli.

Specification

• Description: This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 25 mM Tris, pH 8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
• Molecular Mass: 76.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ARHGAP22 Rho GTPase activating protein 22 [ Homo sapiens ]
• Official Symbol: ARHGAP22
• Synonyms: RhoGAP2; RhoGap22
• Gene ID: 58504
• mRNA Refseq: NM_001256024
• Protein Refseq: NP_001242953
• MIM: 610585
• UniProt ID: Q7Z5H3