| Description : |
This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
| Source : |
Wheat Germ |
| Species : |
Human |
| Tag : |
GST |
| Molecular Mass : |
78.6 kDa |
| AA Sequence : |
MLSPKIRQARRARSKSLVMGEQSRS PGRMPCPHRLGPVLKAGWLKKQRSI MKNWQQRWFVLRGDQLFYYKDKDEI KPQGFISLQGTQVTELPPGPEDPGK HLFEISPGGAGEREKVPANPEALLL MASSQRDMEDWVQAIRRVIWAPLGG GTARRSHAHPLEPLPPGIFGQRLEE TVHHERKYGPRLAPLLVEQCVDFIR ERGLTEEGLFRMPGQANLVRDLQDS FDCGEKPLFDSTTDVHTVASLLKLY LRELPEPVVPFARYEDFLSCAQLLT KDEGEGTLELAKQVSNLPQANYNLL RYICKFLDEVQAYSNVNKMSVQNLA TVFGPNILRPQVEDPVTIMEGTSLV QHLMTVLIRKHSQLFTAPVPEGPTS PRGGLQCAVGWGSEEVTRDSQGEPG GPGLPAHRTSSLDGAAVAVLSRTAP TGPGSRCSPGKKVQTLPSWKSSFRQ PRSLSGSPKGGGSSLEVPIISSGGN WLMNGLSSLRGHRRASSGDRLKDSG SVQRLSTYDNVPAPGLVPGIPSVAS MAWSGASSSESSVGGSLSSCTACRA SDSSARSSLHTDWALEPSPLPSSSE DPKSLDLDHSMDEAGAGASNSEPSE PDSPTREHARRSEALQGLVTELRAE LCRQRTEYERSVKRIEEGSADLRKR MSRLEEELDQEKKKYIMLEIKLRNS ERAREDAERRNQLLQREMEEFFSTL GSLTVGAKGARAPK |
| Applications : |
Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
