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ATG5

  • Official Full Name

    autophagy related 5

  • Overview

    Required for autophagy. Conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed.<br/>May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
  • Synonyms

    ATG5; autophagy related 5; ASP; APG5; APG5L; hAPG5; APG5-LIKE; autophagy protein 5; apoptosis-specific protein; ATG5 autophagy related 5 homolog;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • MYC
  • DDK
  • N/A
  • N
  • T7
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ATG5-26988TH Recombinant Human ATG5, T7 -tagged E.coli T7
Human ATG5-543H Recombinant Human ATG5 Protein E.coli N/A
Human ATG5-5279H Recombinant Human ATG5 Autophagy Related 5 Homolog (S. cerevisiae), T7-tagged E.coli T7
Human ATG5-73H Recombinant Human ATG5 Autophagy Related 5 Homolog, T7-tagged E.coli T7
Human ATG5-951H Recombinant Human ATG5 protein, GST-tagged Wheat Germ GST
Human ATG5-174H Recombinant Human ATG5 protein, T7-tagged E.coli T7
Human ATG5-3425H Recombinant Human ATG5, His-tagged E.coli His
Human APG5L-679H Recombinant Human APG5L protein, GST-tagged Wheat Germ GST
Human ATG5-8622HCL Recombinant Human ATG5 293 Cell Lysate HEK293 N/A
Human ATG5-18H Recombinant Human ATG5 Protein, His-tagged E.coli His 2-275
Human ATG5-020H Recombinant Human ATG5 Protein, His-tagged E. coli His 2-275
Human ATG5-0209H Recombinant Human ATG5 Protein (Met1-Asp275), Tag Free E.coli Tag Free Met1-Asp275
Human ATG5-260H Recombinant Human ATG5 Protein, His-tagged E.coli N-His Met1-Asp275
Human ATG5-1134HF Recombinant Full Length Human ATG5 Protein, GST-tagged In Vitro Cell Free System GST 275 amino acids
Human ATG5-0208H Recombinant Human ATG5 Protein (Met1-Asp275), His-tagged E.coli His Met1-Asp275
Mouse ATG5-2085M Recombinant Mouse ATG5 Protein Mammalian Cell His
Mouse Atg5-624M Recombinant Mouse Atg5 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse ATG5-828M Recombinant Mouse ATG5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse ATG5-828M-B Recombinant Mouse ATG5 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish ATG5-1983Z Recombinant Zebrafish ATG5 Mammalian Cell His
Chicken ATG5-1551C Recombinant Chicken ATG5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ATG5 Related Articles
  • ATG5 Related Research Area

ATG5 involved in several pathways and played different roles in them. We selected most pathways ATG5 participated on our site, such as Regulation of autophagy, RIG-I-like receptor signaling pathway, Shigellosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATG5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Regulation of autophagyATG12;PRKAA1;ULK1;INSB;IFNA17;ATG14;BECN1;IFNA10;IFNA2
RIG-I-like receptor signaling pathwayIL-8;MAPK9;MAPK13;PL10;IFNK;IFNA5;NT5C3;MAPK10;TBKBP1
ShigellosisMAPK9;CDC42;MAPK11;SRC;ELMO2;ELMO3;IKBKB;ITGA5;PFN3

ATG5 has several biochemical functions, for example, contributes_to Atg8 ligase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATG5 itself. We selected most functions ATG5 had, and list some proteins which have the same functions with ATG5. You can find most of the proteins on our site.

Function Related Protein
contributes_to Atg8 ligase activity
protein bindingC17orf81;ELOVL6;ATXN7;HEPACAM2;CATSPERG2;AKR1C1;ZFP2;ABLIM1;CRYBB1

ATG5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATG5 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATG5.

ATG12; WDFY3; ATG16L1; GABARAP; MAP1LC3B

Cai, PP; Wang, HX; et al. Variants of autophagy-related gene 5 are associated with neuromyelitis optica in the Southern Han Chinese population. AUTOIMMUNITY 47:563-566(2014).
Cenci, S; et al. Autophagy, a new determinant of plasma cell differentiation and antibody responses. MOLECULAR IMMUNOLOGY 62:289-295(2014).
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