atp1b3
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  • Official Full Name
  • ATPase, Na+/K+ transporting, beta 3 polypeptide
  • Background
  • The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2.
  • Synonyms
  • ATP1B3; ATPase, Na+/K+ transporting, beta 3 polypeptide; sodium/potassium-transporting ATPase subunit beta-3; CD298; FLJ29027; Na, K-ATPase beta-3 polypeptide; sodium/potassium-dependent ATPase beta-3 subunit; sodium/potassium-dependent ATPase subunit bet
Cat.#:ATP1B3-184HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ATP1B3, His-tagged
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Cat.#:ATP1b3-3767HTag:His|T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ATP1b3, His-tagged, T7 tagged
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Cat.#:ATP1B3-967HTag:N/A
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ATP1B3 protein
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Cat.#:ATP1B3-2118MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ATP1B3 Protein
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Cat.#:Atp1b3-708MTag:His|T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Atp1b3 protein, His & T7-tagged
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Cat.#:Atp1b3-709RTag:His|T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Atp1b3 protein, His & T7-tagged
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Cat.#:ATP1B3-857RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ATP1B3 Protein
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Cat.#:ATP1B3-450RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ATP1B3 Protein, His-tagged
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Cat.#:ATP1B3-7083CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ATP1B3
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Cat.#:ATP1B3-8610HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human ATP1B3 293 Cell Lysate
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Involved Pathway

ATP1B3 involved in several pathways and played different roles in them. We selected most pathways ATP1B3 participated on our site, such as cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP1B3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
cGMP-PKG signaling pathway
CALM2; PLCB2; GUCY1B3; PRKG2; MEF2B; CREB5; PPP3CC; PIK3CG; CALML3; INS1
cAMP signaling pathway
SUCNR1; PPP1CA; PIK3R2; ATP1A3; ATP1B2; FXYD2; GHSR; PRKACG; MAP2K1; PIK3R5
Cardiac muscle contraction
ATP1A2A; UQCRQ; COX7C; TNNT2A; COX4I1; CACNA1DA; CACNB4; UQCRC1; UQCRFS1; CACNG6
Adrenergic signaling in cardiomyocytes
ADCY2B; CALM3A; MYL3; MAPK12B; ATP1B1A; PPP1CC; PLCB4; ADCY1B; CACNG7A; PRKACAB
Insulin secretion
CAMK2D; ITPR3; PLCB2; SLC2A2; ATP1A2; INS2; GNAQ; KCNJ11; PRKACB; KCNN3
Thyroid hormone synthesis
DUOX2; PRKCB; GPX7; FXYD2; CREB3L2; GPX8; CREB3L1; GNAQ; ATP1A1; ASGR1
Thyroid hormone signaling pathway
MAPK1; GATA4; PLCB1; MED30; HIF1A; DIO2; PRKCG; NCOR1; MTOR; PLCD4
Aldosterone-regulated sodium reabsorption
PIK3CD; ATP1A4; INSR; KRAS; ATP1A2; MAPK1; NR3C2; HSD11B2; PRKCB; ATP1A3
Endocrine and other factor-regulated calcium reabsorption
KLK1B26; PRKCB; SLC8A1; KLK1B11; PRKCA; PRKACA; PLCB3; BDKRB2; ATP1B1; KL
Proximal tubule bicarbonate reclamation
MDH1; ATP1B3; PCK2; SLC25A10; ATP1A3; SLC38A3; AQP1; ATP1A4; Car4; CA2
Salivary secretion
ATP1A2; Adcy4; GNAQ; CALML5; LPO; PRKG1; PRB1; CD38; KCNN4; ATP1B3
Gastric acid secretion
GNAI3; CALML3; PRKACA; KCNJ15; MYLK4; ATP1A1; PRKCG; ATP4B; ATP4A; PRKACG
Pancreatic secretion
CD38; BST1; ATP1B1; ATP1B3; SLC9A1; PLA2G5; PRSS3; RAC1; CTRB1; ATP2A1
Carbohydrate digestion and absorption
PIK3R2; ATP1B1; HK1; SLC2A5; AKT2; PIK3CG; PIK3CA; ATP1B4; AMY1B; AMY2A
Protein digestion and absorption
SLC1A5; FXYD2; ATP1B3; ATP1A3; CELA3A; XPNPEP2; PRSS2; ATP1B1; ATP1B2; COL7A1
Bile secretion
EPHX1; SCTR; SLC22A7; ATP1A1; ATP1A2; ABCG2; SLCO1B1; GNAS; SLCO1A5; AQP9
Mineral absorption
MT1F; SLC9A3; SLC8A1; SLC31A1; SLC11A2; STEAP2; FTH1; MT1; SLC26A9; ATP1A1

Protein Function

ATP1B3 has several biochemical functions, for example, ATPase activator activity, ATPase binding, sodium:potassium-exchanging ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP1B3 itself. We selected most functions ATP1B3 had, and list some proteins which have the same functions with ATP1B3. You can find most of the proteins on our site.
Function
Related Protein
Function ATPase activator activity
Related Protein MYBPC3; DNAJC24; ATP1B1; TOR1AIP1; ATP1B2; AHSA2; TOR1AIP2; DNAJB6; DNAJC19; DNAJC15
Function ATPase binding
Related Protein S100A1; SELS; FXYD1; ATP6V0A1A; CHRNA7; ATPIF1; FXYD4; ANK2; NSFL1C; ATP6V0A4
Function sodium:potassium-exchanging ATPase activity
Related Protein ATP1A3; ATP1A2A; ATP1A1A.5; ATP1A4; ATP1B3; ATP12A; ATP1A1B; ATP1A3B; FXYD2; ATP1A1
Function contributes_to sodium:potassium-exchanging ATPase activity
Related Protein ATP1A1; ATP1A2; ATP1B1; ATP1B2; ATP1B3

Interacting Protein

ATP1B3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP1B3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP1B3.
PTP4A3; b3xyc5_sollc; cona_canen; 1C; P