Recombinant Human ATP1B3 Protein, His-tagged

• Cat.No.: ATP1B3-151H
• Product Overview: Recombinant Human ATPase Na+/K+ transporting subunit beta 3(ATP1B3)(NM_001679), with a His tag, was expressed in human cells.

Specification

• Description: The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2.
• Source: Human Cells
• Species: Human
• Tag: His
• Form: Purified protein formulated in a sterile solution of TBS buffer, pH7.180, without any preservatives.
• Molecular Mass: 31.3 kDa
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
• Purity: >90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.

Gene Information

• Gene Name: ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide [ Homo sapiens ]
• Official Symbol: ATP1B3
• Synonyms: ATP1B3; ATPase, Na+/K+ transporting, beta 3 polypeptide; sodium/potassium-transporting ATPase subunit beta-3; CD298; FLJ29027; Na, K-ATPase beta-3 polypeptide; sodium/potassium-dependent ATPase beta-3 subunit; sodium/potassium-dependent ATPase subunit beta-3; sodium/potassium-transporting ATPase beta-3 chain; ATPB-3
• Gene ID: 483
• mRNA Refseq: NM_001679
• Protein Refseq: NP_001670
• MIM: 601867
• UniProt ID: P54709