BMP8B Protein, bone morphogenetic protein 8b

BMP8B

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BMP8B

Official Full Name bone morphogenetic protein 8b
Background The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity.
Synonyms BMP8B; bone morphogenetic protein 8b; BMP8, bone morphogenetic protein 8 (osteogenic protein 2); OP 2; osteogenic protein 2; BMP-8; BMP-8B; BMP8B_HUMAN; Bone morphogenetic protein 8; OP-2; OP2; OTTHUMP00000010836; bone morphogenetic protein 8 (osteogenic protein 2); dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)); BMP8
    • Species :
    • Human
    • Mouse
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • His
    • SUMO
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse BMP8B-2692M Recombinant Mouse BMP8B Protein (261-399 aa), His-SUMO-tagged E.coli His/SUMO
    Human BMP8B-18H Recombinant Human BMP8B, His-tagged E.coli His
    Human BMP8B-230H Recombinant Human BMP8B protein CHO N/A
    Human BMP8B-250H Recombinant Human BMP8B, His-tagged E.coli His
    Human BMP8B-27490TH Recombinant Human BMP8B Wheat Germ N/A
    Human BMP8B-8428HCL Recombinant Human BMP8B 293 Cell Lysate HEK293 N/A
    Mouse BMP8B-2436M Recombinant Mouse BMP8B Protein Mammalian Cell His

    BMP8B involved in several pathways and played different roles in them. We selected most pathways BMP8B participated on our site, such as TGF-beta signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with BMP8B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    TGF-beta signaling pathway INHBE; INHBB; MYCB; BMP8A; BMP7B; BMPR1B; AMHR2; ROCK1; PPP2R1B; LEFTY2
    Hippo signaling pathway ID2; ITGB2L; WWTR1; APC; PRKCI; CDH1; SMAD7; WNT5A; WNT8A; AFP

    BMP8B has several biochemical functions, for example, BMP receptor binding, cytokine activity, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BMP8B itself. We selected most functions BMP8B had, and list some proteins which have the same functions with BMP8B. You can find most of the proteins on our site.

    Function Related Protein
    BMP receptor binding BMP7A; BMP8A; BMP7; BMP4; BMP8B; BMP2B; PYCARD; BMP7B; BMP3; BMP2
    cytokine activity CD70; CCL20B; TNFSF13; IFNA6; IL17D; GREM1; SLURP1; WNT1; FLT3LG; IFNK
    growth factor activity JAG2; GDNFA; BMP1; GMFB; CXCL12; INHBC; GDF3; IL5; PDGFA; HBEGFA
    transforming growth factor beta receptor binding GDF10B; BMP8A; LFT1; BMP3; LFT2; GDF1; GDF6; GDF9; SMURF2; BMP15

    BMP8B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BMP8B here. Most of them are supplied by our site. Hope this information will be useful for your research of BMP8B.

    WFIKKN2; WFIKKN1; ABL1; FYN

    TGF

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