Active Recombinant Human BMP8B Protein
Cat.No. : | BMP8B-018H |
Product Overview : | The mature recombinant human BMP-8b protein consists of 139 amino acids (264-402) without tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. |
Source : | E. coli |
Species : | Human |
Bio-activity : | Measured by its ability to inhibit the cell growth of DU145 human prostate carcinoma cells. The ED50 for this effect is 0.7-3.5 μg/mL. |
Molecular Mass : | 16 kDa |
Product-Related Proteins : | 264-402 |
Endotoxin : | < 0.1 EU/μg of the protein as determined by the LAL method |
Purity : | > 95 % as determined by SDS-PAGE |
Storage : | At -80 centigrade. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | PBS |
Gene Name : | BMP8B bone morphogenetic protein 8b [ Homo sapiens (human) ] |
Official Symbol : | BMP8B |
Synonyms : | BMP8B; bone morphogenetic protein 8b; OP2; BMP8; bone morphogenetic protein 8B; Names; bone morphogenetic protein 8 (osteogenic protein 2); osteogenic protein 2 |
Gene ID : | 656 |
mRNA Refseq : | NM_001720 |
Protein Refseq : | NP_001711 |
MIM : | 602284 |
UniProt ID : | P34820 |
Products Types
◆ Recombinant Protein | ||
BMP8B-1056M | Recombinant Mouse BMP8B Protein, His (Fc)-Avi-tagged | +Inquiry |
BMP8B-19H | Recombinant Active Human BMP8B Protein, His-tagged(N-ter) | +Inquiry |
BMP8B-2692M | Recombinant Mouse BMP8B Protein (261-399 aa), His-SUMO-tagged | +Inquiry |
BMP8B-283H | Active Recombinant Human BMP8B Protein (Ala264-His402), N-His tagged, Animal-free, Carrier-free | +Inquiry |
BMP8B-2436M | Recombinant Mouse BMP8B Protein | +Inquiry |
◆ Lysates | ||
BMP8B-8428HCL | Recombinant Human BMP8B 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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