BMPR1B
-
Official Full Name
bone morphogenetic protein receptor, type IB
-
Overview
Bone morphogenetic proteins (BMP); are members of the transforming growth factor beta (TGF-beta); superfamily and are involved in a wide variety of biological processes, including osteoblast differentiation and bone healing. The activities of the BMP are -
Synonyms
BMPR1B; bone morphogenetic protein receptor, type IB; bone morphogenetic protein receptor type-1B; ALK6; CDw293; BMPR-1B; BMP type-1B receptor; activin receptor-like kinase 6; serine/threonine receptor kinase; ALK-6;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rhesus Macaque
- E.coli
- E.coli expression system
- HEK293
- Human Cell
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Mammalian cells
- Sf21 Insect Cell
- Sf9 Insect Cell
- Wheat Germ
- C
- His
- Fc
- Fc|His
- GST
- His (Fc)
- Avi
- His|GST
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- BMPR1B Related Gene Family
BMPR1B involved in several pathways and played different roles in them. We selected most pathways BMPR1B participated on our site, such as Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with BMPR1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Cytokine-cytokine receptor interaction | INHBB;GH2;CCR1L1;PDGFAB;CCR6A;MET;IL7R;IFNA5;CCR6 |
TGF-beta signaling pathway | INHBE;BMPR2;INHBA;SMAD3A;AMH;ACVR2B;NOG;RHOA;LEFTY2 |
Hippo signaling pathway | BMP7;CRB2;PPP1CB;PPP2CB;LATS2;SMAD2;WNT3;LIMD1;DVL3 |
Signaling pathways regulating pluripotency of stem cells | ISL1;PIK3R5;WNT11;FZD3;SMAD1;BMI1;WNT9A;LHX5;WNT16 |
BMPR1B has several biochemical functions, for example, ATP binding, SMAD binding, glycoprotein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BMPR1B itself. We selected most functions BMPR1B had, and list some proteins which have the same functions with BMPR1B. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
ATP binding | MAPK4;SYN2B;GRK7A;TRPM4;EIF2B2;MYLK3;HNRNPU;CLCN6;AK7 |
SMAD binding | TOB1;ACVR1B;EID2;HIPK2;PURA;BMP2;TCF12;FKBP1A;STUB1 |
glycoprotein binding | FBXO2;CD4;TGFB1;Serpina1c;LRRK2;IGF2R;BMPR1B;HSPA5;SHB |
metal ion binding | TROVE2;NRAP;ZNF839;ME2;ARFGAP2;OVCH2;BCL6A;MBNL2;ZSCAN21 |
protein binding | CD22;SIAH1;DNAJB11;LTBP2;BET1;TLE1;NEDD4L;HSPB9;CCDC88A |
protein serine/threonine kinase activity | RPS6KA5;PSKH2;BMPR2B;MAP2K3;MKNK2;NUAK2;MKNK1;PRKD2;MAP3K13 |
receptor signaling protein serine/threonine kinase activity | ACVR1B;PANK1A;STK25B;BMPR1B;PAK2A;BMPR1A;TGFBR1;STK26;ACVR1BA |
transforming growth factor beta receptor activity, type I | TGFBR1;ACVR1;BMPR1B |
transmembrane receptor protein serine/threonine kinase activity | BMPR1B;BMPR2B;ACVR2AA;ACVR2A;ACVR1;ALPK2;BMPR1AA;TGFBR2;BMPR1BB |
BMPR1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BMPR1B here. Most of them are supplied by our site. Hope this information will be useful for your research of BMPR1B.
GDF5; BMP2; Dlg4; Rhod; Sash3; Chn1; Ubxn1; Lztr1; Fancl; Rhebl1; Plekhb1
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, the role of BMPR1B in tissue regeneration, especially in bone and cartilage, makes it a potential target for regenerative medicine approaches.
Therapeutic strategies may involve the use of small molecules, antibodies, or gene therapies to modulate BMPR1B activity for treating various clinical conditions.
BMPR1B is involved in the regulation of ovarian function and follicular development, making it relevant to fertility treatments and reproductive medicine.
BMPR1B is involved in neural development, and understanding its role could have implications for neuroregenerative medicine and the treatment of neurodevelopmental disorders.
While the direct association with autoimmune diseases is not well-established, the role of BMPR1B in immune regulation might be explored for potential implications in autoimmune disorders.
Customer Reviews (3)
Write a reviewGreat performance in ELISA.
Researchers can confidently rely on this high-quality protein to produce accurate and reproducible results, thereby accelerating their research progress
Its well-established reputation and reliability further contribute to its suitability for a wide range of experimental designs.
Ask a Question for All BMPR1B Products
Required fields are marked with *
My Review for All BMPR1B Products
Required fields are marked with *