| Official Full Name | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| Background | BMPR2 is a type II serine/threonine receptor kinase that binds to an array of secreted bone morphogenetic proteins (BMPs). BMPs belong to the superfamily of TGF-beta ligands that modulate gastrulation, neurogenesis, chondrogenesis, interdigital cell death |
| Synonyms | BMPR2; bone morphogenetic protein receptor, type II (serine/threonine kinase); PPH1, primary pulmonary hypertension 1; bone morphogenetic protein receptor type-2; BMPR II; BMPR3; BRK 3; T ALK; BMPR-2; BMP type-2 receptor; BMP type II receptor; type II ac |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Bmpr2 involved in several pathways and played different roles in them. We selected most pathways Bmpr2 participated on our site, such as Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Bmpr2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine-cytokine receptor interaction | TNFRSF19; LIF; CXCL12A; IL17RA; TGFB2; CCR5; IFNGR1; CXCL5; CXCL8; CCR1 |
| TGF-beta signaling pathway | PITX2; BAMBI; TNF; RHOAC; MAPK3; FSTA; ACVR1B; ZFYVE9; ACVR1BA; BMP8B |
| Hippo signaling pathway | GDF7; YWHAH; DVL3; GSK3B; WTIP; RASSF1; NKD1; WNT3A; LEF1; CTGF |
| Signaling pathways regulating pluripotency of stem cells | SOX2; PCGF1; HNF1A; ISL1; GSK3B; BMPR1A; AKT2; ESX1; PCGF6; TCF3 |
| MicroRNAs in cancer | TNC; FGFR3; SERPINB5; PTGS2; PRKCG; KIF23; ST14; MTOR; RAF1; Abcb1b |
Bmpr2 has several biochemical functions, for example, ATP binding, BMP binding, activin receptor activity, type II. Some of the functions are cooperated with other proteins, some of the functions could acted by Bmpr2 itself. We selected most functions Bmpr2 had, and list some proteins which have the same functions with Bmpr2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | FLT3; RPS6KA4; TPK1; MAPK14; PAPOLG; Acsm2a; MYO7AA; ATP1A1A.1; ABCF2A; PRPF4BA |
| BMP binding | HFE2; TCAP; GREM1; CER1; GDF5; BMPR2; NBL1; GREM2 |
| activin receptor activity, type II | BMPR2 |
| growth factor binding | NKD2; ACVR2A; HTRA1A; IL6ST; RPL37; ACVR1C; GHRHR; BMPR2; REG3B; FLT4 |
| metal ion binding | FBXO40.1; PDE4B; ZNF501; JADE1; XIRP2; CYBRD1; ZNF511; GALNT4; DMRTA1; CYP2D26 |
| protein binding | CREBZF; INPP5K; AURKA; IL6ST; MAP3K7IP3; MAGEH1; TECPR1; NFATC4; TTC17; LRRK2 |
| receptor signaling protein serine/threonine kinase activity | BMPR1AA; STK24A; OXSR1B; STK39; TGFB2; ACVR2B; STK25A; TGFBR2; ACVR2AA; TGFBR1A |
Bmpr2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Bmpr2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Bmpr2.
PRKG1; C4bpa; Prkcb; GDF5; MAPK8; Bmpr2; Ctbp1; Mos; Serpina3k; Lsp1; Cryab
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