|Official Full Name||chibby homolog 1 (Drosophila)|
|Background||Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.|
|Synonyms||CBY; arb1; PGEA1; C22orf2; PIGEA14; PIGEA-14; HS508I15A|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CBY1 involved in several pathways and played different roles in them. We selected most pathways CBY1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with CBY1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Deactivation of the beta-catenin transactivating complex||ASH2L; SOX13; SOX32; TLE2; RBBP5; CTBP1; BCL9L; TLE3; PYGO2; CBY1|
|Regulation of Wnt-mediated beta catenin signaling and target gene transcription||CDX1; CBY1; MYOG; KRT1; TLE4; ZCCHC12; BCL9; HBP1; TCF4; T|
|Signal Transduction||CDC73; MYO7AA; PRC1; RHPN1; JUPA; EVC; TNKS2; HCAR1-2; PLEKHG2; GPR132B|
|Signaling by Wnt||PYGO2; DACT1; PYGO1; CSNK1G2; WIF1; CCDC88C; SOX7; KREMEN1; TNKS2; RNF43|
|TCF dependent signaling in response to WNT||RNF146; ASH2L; PYGO1; TNKS; TNKS2; RSPO4; C; CDC73; RSPO2; RYK|
CBY1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by CBY1 itself. We selected most functions CBY1 had, and list some proteins which have the same functions with CBY1. You can find most of the proteins on our site.
|beta-catenin binding||NF2; DACT1; BTRC; AXIN2; SALL1; CTNNA3; TCF7L2; CD2AP; CALCOCO1; TBL1XR1|
|identical protein binding||GCG; ACTG1; BAK1; NONO; IFI16; GCC2; ETNPPL; B2M; SDK2; RUVBL2|
|protein binding||DDX21; MEX3C; HNF4A; KLKB1; CRHR2; NUDT1; SPTLC1; OLFM4; CAV1; SPRYD7|
CBY1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CBY1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CBY1.
FAM92A1; TTC23L; CFAP53; YWHAZ; CDK6; q81xy2_bacan; sbcC3; AGTPBP1; q9wmx2-pro_0000037548; YWHAE