Recombinant Human CBY1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CBY1-1582H
• Product Overview: CBY1 MS Standard C13 and N15-labeled recombinant protein (NP_056188) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 14.3 kDa
• AA Sequence: MPFFGNTFSPKKTPPRKSASLSNLH SLDRSTREVELGLEYGSPTMNLAGQ SLKFENGQWIAETGVSGGVDRREVQ RLRRRNQQLEEENNLLRLKVDILLD MLSESTAESHLMEKELDELRISRKR KSGPTRTRRLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CBY1 chibby family member 1, beta catenin antagonist [ Homo sapiens (human) ]
• Official Symbol: CBY1
• Synonyms: CBY1; chibby family member 1, beta catenin antagonist; CBY; arb1; PGEA1; C22orf2; Chibby1; PIGEA14; PIGEA-14; HS508I15A; protein chibby homolog 1; ARPP-binding protein; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1; chibby CTNNB1-mediated transcription inhibitor; chibby homolog 1; coiled-coil protein PIGEA-14; cytosolic leucine-rich protein; polycystin-2 interactor, Golgi- and endoplasmic reticulum-associated protein, 14 kDa
• Gene ID: 25776
• mRNA Refseq: NM_015373
• Protein Refseq: NP_056188
• MIM: 607757
• UniProt ID: Q9Y3M2