Recombinant Human CBY1 Protein (Lys12-Glu115), His tagged

• Cat.No.: CBY1-1388H
• Product Overview: Recombinant human CBY1 (Lys12-Glu115) fused with His tag was expressed in E. coli.

Specification

• Description: Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 13.86 kDa
• Protein Length: Lys12-Glu115
• Purity: >90% as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles.
  Store at 2 to 8 centigrade for one week.
  Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: CBY1 chibby 1, beta catenin antagonist [ Homo sapiens (human) ]
• Official Symbol: CBY1
• Synonyms: CBY1; chibby 1, beta catenin antagonist; CBY; arb1; PGEA1; C22orf2; Chibby1; PIGEA14; PIGEA-14; HS508I15A; protein chibby homolog 1; ARPP-binding protein; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1; chibby CTNNB1-mediated transcription inhibitor; chibby family member 1, beta catenin antagonist; chibby homolog 1; coiled-coil protein PIGEA-14; cytosolic leucine-rich protein; polycystin-2 interactor, Golgi- and endoplasmic reticulum-associated protein, 14 kDa
• Gene ID: 25776
• mRNA Refseq: NM_015373
• Protein Refseq: NP_056188
• MIM: 607757
• UniProt ID: Q9Y3M2