Recombinant Human CBY1 Protein, GST-tagged

• Cat.No.: CBY1-5152H
• Product Overview: Human CBY1 full-length ORF ( NP_001002880.1, 1 a.a. - 126 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 40.9 kDa
• AA Sequence: MPFFGNTFSPKKTPPRKSASLSNLH SLDRSTREVELGLEYGSPTMNLAGQ SLKFENGQWIAETGVSGGVDRREVQ RLRRRNQQLEEENNLLRLKVDILLD MLSESTAESHLMEKELDELRISRKR K
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CBY1 chibby family member 1, beta catenin antagonist [ Homo sapiens (human) ]
• Official Symbol: CBY1
• Synonyms: CBY1; chibby family member 1, beta catenin antagonist; CBY; arb1; PGEA1; C22orf2; PIGEA14; PIGEA-14; HS508I15A; protein chibby homolog 1; ARPP-binding protein; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1; chibby CTNNB1-mediated transcription inhibitor; chibby homolog 1; coiled-coil protein PIGEA-14; cytosolic leucine-rich protein; polycystin-2 interactor, Golgi- and endoplasmic reticulum-associated protein, 14 kDa
• Gene ID: 25776
• mRNA Refseq: NM_001002880
• Protein Refseq: NP_001002880
• MIM: 607757
• UniProt ID: Q9Y3M2