Recombinant Mouse Cby1 Protein, Myc/DDK-tagged

• Cat.No.: Cby1-1978M
• Product Overview: Purified recombinant protein of mouse full-length chibby family member 1, beta catenin antagonist (Cby1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.
• Molecular Mass: 14.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cby1 chibby family member 1, beta catenin antagonist [ Mus musculus (house mouse) ]
• Official Symbol: Cby1
• Synonyms: Cby1; chibby family member 1, beta catenin antagonist; ar; CBY; Pge; PGEA; arb1; Pgea1; PGEA14; 1110014P06Rik; protein chibby homolog 1; PIGEA-14; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1; PKD2 interactor, golgi and endoplasmic reticulum associated 1; chibby homolog 1; cytosolic leucine-rich protein
• Gene ID: 73739
• mRNA Refseq: NM_028634
• Protein Refseq: NP_082910
• UniProt ID: Q9D1C2