ccl24
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  • Official Full Name
  • chemokine (C-C motif) ligand 24
  • Background
  • C-C motif chemokine 24 (CCL24), also known as Eotaxin-2 and MPIF-2, is a 119 amino acid secreted protein that is found in activated monocytes and activated T lymphocytes. After signal sequence processing and maturation, it becomes 93 amino acids long (27 to 119). CCL 24 belongs to the intercrine beta (chemokine CC) family and is N- glycosylated after post-translational modification. It serves as a chemotactic factor for resting T-lymphocytes, and eosinophils. CCL24 has a lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. It is a strong suppressor of colony formation by a multi-potential hematopoietic progenitor cell line. CCL24 binds to CCR3.
  • Synonyms
  • Ckb-6; MPIF-2; MPIF2; SCYA24; C-C motif chemokine 24; CK-beta-6; eosinophil chemotactic protein 2; eotaxin-2; myeloid progenitor inhibitory factor 2; small inducible cytokine subfamily A (Cys-Cys), member 24; small-inducible cytokine A24
Cat.#:CCL24-0629HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CCL24 Protein, GST-Tagged
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Cat.#:CCL24-357HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Chemokine (C-C motif) Ligand 24
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Cat.#:Ccl24-475MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Chemokine (C-C motif) Ligand 24
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Cat.#:CCL24-035HTag:His
Source (Host):HEK293 cellSpecies:Human
Product nameRecombinant Human CCL24 Protein, His-tagged
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Cat.#:CCL24-101HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Chemokine (C-C motif) Ligand 24, HIgG1 Fc-tagged, mutant
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Cat.#:CCL24-102HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Chemokine (C-C motif) Ligand 24, MIgG2a Fc-tagged
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Cat.#:CCL24-103HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Chemokine (C-C motif) Ligand 24, HIgG1 Fc-tagged
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Cat.#:CCL24-138HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CCL24, Fc-tagged
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Cat.#:CCL24-207HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CCL24
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Cat.#:CCL24-258HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CCL24 Protein, His-tagged
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Cat.#:CCL24-816HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CCL24 protein, His-tagged
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Cat.#:Ccl24-817MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ccl24 protein, His-tagged
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Cat.#:Ccl24-638RTag:
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ccl24
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Cat.#:Ccl24-818RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ccl24 protein, His-tagged
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Cat.#:CCL24-687RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CCL24 Protein, His-tagged
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Cat.#:CCL24-437HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CCL24 cell lysate
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Involved Pathway

CCL24 involved in several pathways and played different roles in them. We selected most pathways CCL24 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL24 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
TGFB2; IL17RB; CCL22; FAS; LIFRA; IL9; IL12A; IL11RA; IL11RA2; CCL20
Chemokine signaling pathway
RELA; ROCK2; HRAS; GNB2; CCL21; CCL4; GNG12; PIK3CA; CCL14; Ccl21c

Protein Function

CCL24 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL24 itself. We selected most functions CCL24 had, and list some proteins which have the same functions with CCL24. You can find most of the proteins on our site.
Function
Related Protein
Function CCR chemokine receptor binding
Related Protein CCL14; CCL11; CCL35.1; CCL38A.4; CCL34A.4; CCL38A.5; CCL21; CCL19; CCL18; CCL19A.1
Function chemokine activity
Related Protein CXCL12; PF4V1; CXCL12B; CCL35.1; CCL34A.4; PF4; AMCF-II; CCL34B.9; CCL34B.4; Ccl9

CCL24 Related Articles

Makita, N; Hizukuri, Y; et al. IL-10 enhances the phenotype of M2 macrophages induced by IL-4 and confers the ability to increase eosinophil migration. INTERNATIONAL IMMUNOLOGY 27:131-141(2015).
Huang, XS; Gruner, B; et al. Distinctive cytokine, chemokine, and antibody responses in Echinococcus multilocularis-infected patients with cured, stable, or progressive disease. MEDICAL MICROBIOLOGY AND IMMUNOLOGY 203:185-193(2014).

CCL24 Related Gene Family

Chemokines Cytokines