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Recombinant Rat Ccl24 protein
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Cat.No. : | Ccl24-638R Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Rat Ccl24 protein was expressed in Escherichia coli. |
Description : | CCL24, also named MPIF-2, Eotaxin-2 and Ckβ6, is a novel CC chemokine recently identified. It is a secreted protein, encoded by CCL24 gene, and produced by activated monocytes and T lymphocytes. CCL24 signals through the CCR3 receptor and has functions of chemotactic activity for resting T-lymphocytes and eosinophils, but none for monocytes and activated lymphocytes. The plasma levels of CCL24 and the aspirin-exacerbated respiratory disease (such as asthma) morbidity rate have positive correlation. |
Source : | E.coli |
Species : | Rat |
Form : | Lyophilized from a 0.2μm filtered concentrated solution in 2 × PBS, pH 7.4. |
Bio-activity : | Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human peripheral blood eosinophils is in a concentration of 50-250 ng/ml. |
Molecular Mass : | Approximately 10.5 kDa, a single non-glycosylated polypeptide chain consisting of an N-terminal Methionine and the mature rat Eotaxin-2. |
Protein length : | 98 |
AA Sequence : | MPTGSVTIPS SCCVTFISKK IPVNRVISYQ LANGSICPKA GVIFITKKGH KICTDPKLPW VQKHIKNLDA KRNQPSEGAK ALGPKFVIQK LRGNSTKV |
Endotoxin : | Less than 1 EU/µg of rRtEotaxin-2/CCL24 as determined by LAL method. |
Purity : | >96% by SDS-PAGE and HPLC analysis. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions. |
SDS-PAGE of Ccl24-638R : |
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Gene Name : | Ccl24 |
Official Symbol : | Ccl24 |
Synonyms : | CCL24; chemokine (C-C motif) ligand 24; C-C motif chemokine 24; eotaxin-2; eotaxin-2-like protein; eosinophil chemotactic protein 2; |
Gene ID : | 288593 |
mRNA Refseq : | NM_001013045 |
Protein Refseq : | NP_001013063 |
UniProt ID : | Q5PPP2 |
◆ Recombinant Protein
CCL24-0629H | Recombinant Human CCL24 Protein, GST-Tagged | +Inquiry |
Ccl24-151M | Recombinant Mouse Ccl24 Protein | +Inquiry |
Ccl24-1348M | Recombinant Mouse Ccl24 Protein | +Inquiry |
CCL24-51H | Recombinant Human CCL24 Protein | +Inquiry |
CCL24-035H | Recombinant Human CCL24 Protein, His-tagged | +Inquiry |
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◆ Lysates
CCL24-437HCL | Recombinant Human CCL24 cell lysate | +Inquiry |
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CCL1CCL11Ccl12CCL13CCL14CCL15CCL16CCL17CCL18CCL19CCL2CCL20CCL21Ccl21cCCL22CCL23CCL24CCL25CCL26CCL27Ccl27aCCL28CCL3CCL3L1Ccl4CCL5Ccl6CCL7CCL8Ccl9CCL4L2Ccl21aCCL4L1CCL3L3Ccl21bCcl27b
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