CD53 Protein, Cd53 molecule

CD53

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CD53

Official Full Name Cd53 molecule
Background The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family.;Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains.;The proteins mediate signal transduction events that play a role in the regulation of cell development, activation,;growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It;contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to;play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated;with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple;transcript variants encoding the same protein.
Synonyms CD53; Cd53 molecule; leukocyte surface antigen CD53; CD53 antigen; Leukocyte antigen (Ox-44); leukocyte antigen MRC OX-44; cell surface glycoprotein CD53; OX44; Ox-44; RATOX44
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Source :
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • His
    • GST
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CD53-0832H Recombinant Human CD53 Protein Wheat Germ N/A
    Human CD53-0833H Recombinant Human CD53 Protein, GST-Tagged Wheat Germ GST
    Human CD53-3094H Recombinant Human CD53 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse CD53-158M Recombinant Mouse Cd53, His tagged Human Cell Fc
    Mouse CD53-808MCL Recombinant Mouse CD53 cell lysate Human Cell N/A
    Rat CD53-1259R Recombinant Rat CD53 Protein Mammalian Cell His
    Cynomolgus Monkey CD53-1018CCL Recombinant Cynomolgus CD53 cell lysate Human Cell N/A
    Cynomolgus Monkey CD53-1122CCL Recombinant Cynomolgus CD53 cell lysate Human Cell N/A
    Cynomolgus Monkey CD53-98C Recombinant Cynomolgus CD53, Fc tagged Human Cell Fc/His
    Cynomolgus Monkey CD53-99C Recombinant Cynomolgus CD53, His tagged Human Cell N/A
    Cynomolgus Monkey CD58-100C Rcombinant Cynomolgus CD58, His-tagged Human Cell His

    CD53 involved in several pathways and played different roles in them. We selected most pathways CD53 participated on our site, such as IL-2 Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD53 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    IL-2 Signaling Pathway NMI; CD53; SHB; CISH; ITM2BA

    CD53 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CD53 itself. We selected most functions CD53 had, and list some proteins which have the same functions with CD53. You can find most of the proteins on our site.

    Function Related Protein

    CD53 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD53 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD53.

    Todros-Dawda, I; Kveberg, L; et al. The Tetraspanin CD53 Modulates Responses from Activating NK Cell Receptors, Promoting LFA-1 Activation and Dampening NK Cell Effector Functions. PLOS ONE 9:-(2014).
    Ruiz-Mateos, E; Pelchen-Matthews, A; et al. CD63 is not required for production of infectious human immunodeficiency virus type 1 in human macrophages. JOURNAL OF VIROLOGY 82:4751-4761(2008).

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