CDH2 Protein, cadherin 2, type 1, N-cadherin (neuronal)


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Official Full Name cadherin 2, type 1, N-cadherin (neuronal)
Background This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. [provided by RefSeq, Jul 2008]
Synonyms CDH2; cadherin 2, type 1, N-cadherin (neuronal); CDHN; NCAD; CD325; CDw325; cadherin-2; N-cadherin 1; neural cadherin; neural-cadherin; cadherin 2, N-cadherin (neuronal); calcium-dependent adhesion protein, neuronal;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus monkey
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • NS0
    • Rabbit
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • hIgG1
    • hIgG4
    • His
    • Flag
    • StrepII
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Cdh2-861M Recombinant Mouse Cdh2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human CAB11508RH Rabbit Anti-Human Cadherin 2, type 1, N-cadherin Monoclonal Antibody Rabbit N/A
    Human CDH2-0983H Recombinant Human CDH2 Protein, His-Flag-StrepII-Tagged Human Cell His/Flag/StrepII
    Human CDH2-0984H Recombinant Human CDH2 Protein, GST-Tagged Wheat Germ GST
    Human CDH2-2191H Recombinant Human CDH2, His tagged Human Cell His
    Human CDH2-271H Recombinant Human CDH2 Protein, His-tagged Insect Cell His
    Human CDH2-28769TH Recombinant Human CDH2 Wheat Germ N/A
    Human CDH2-3153H Recombinant Human CDH2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CDH2-315H Recombinant Human CDH2, His-Fc tagged Human Cell Fc
    Human CDH2-316H Recombinant Human CDH2, Fc tagged NS0 Fc
    Human CDH2-4938H Recombinant Human CDH2 protein, GST-tagged E.coli GST
    Human CDH2-7023H Recombinant Human CDH2 protein, His-tagged E.coli His
    Human CDH2-87H Recombinant Human Cadherin 2, Type 1, N-cadherin (Neuronal) E.coli N/A
    Human CDH2-980HCL Recombinant Human CDH2 cell lysate Human Cell N/A
    Mouse CDH2-304M Recombinant Mouse Cdh2, LEVLFQ tagged Human Cell His
    Mouse Cdh2-592M Recombinant Mouse Cdh2 Protein, Fc Chimera NS0 Fc
    Mouse Cdh2-7024M Recombinant Mouse Cdh2 protein, His-tagged E.coli His
    Mouse CDH2-971MCL Recombinant Mouse CDH2 cell lysate Human Cell N/A
    Rat CDH2-1290R Recombinant Rat CDH2 Protein Mammalian Cell His
    Rat Cdh2-7025R Recombinant Rat Cdh2 protein, His-tagged E.coli His
    Rat Cdh2-7026R Recombinant Rat Cdh2 protein, His-tagged E.coli His
    Rat Cdh2-8757R Recombinant Rat Cdh2, His tagged Human Cell His
    Rhesus monkey CDH2-1740R Recombinant Rhesus Monkey CDH2 Protein HEK293 N/A
    Rhesus monkey CDH2-1741R Recombinant Rhesus Monkey CDH2 Protein, hIgG1-tagged HEK293 hIgG1
    Rhesus monkey CDH2-1742R Recombinant Rhesus Monkey CDH2 Protein, hIgG4-tagged HEK293 hIgG4
    Chicken CDH2-1134C Recombinant Chicken CDH2 Mammalian Cell His
    Zebrafish CDH2-8707Z Recombinant Zebrafish CDH2 Mammalian Cell His

    CDH2 involved in several pathways and played different roles in them. We selected most pathways CDH2 participated on our site, such as Adherens junctions interactions, Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy (ARVC), which may be useful for your reference. Also, other proteins which involved in the same pathway with CDH2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adherens junctions interactions CDH17; CDH10A; CDH12; CTNNA1; CDH3; CDH24; CDH2; CDH9; CADM2B; CDH8
    Arrhythmogenic right ventricular cardiomyopathy DSG2; JUP; CTNNA2; CDH2; CACNG3; DSC2; CACNG2; DES; DAG1; DMD
    Arrhythmogenic right ventricular cardiomyopathy (ARVC) DES; SGCA; ITGA7; SGCG; CACNA2D4; CACNG4; ITGA3; ATP2A2; LEF1; ACTN3
    BDNF signaling pathway EGR1; DOK5; CDKL5; MAP3K2; FRS3; CNR1; GNB2L1; SIRPA; EIF4E; IGF2BP1
    CDO in myogenesis CTNNA1; TCF3B; BOC; CTNNA2; SPAG9; MYOD1; CDON; MEF2AA; BNIP2; CDH4
    Cell adhesion molecules (CAMs) CD99; MHC2DCB; NLGN4A; ICAM1; CD4; HLA-E; CD6; SELP; CLDNG; PECAM1
    Cell junction organization PVRL1A; CDH12A; PLECA; CDH9; CLDN7; CADM2; CTNND1; CDH10A; CDH7; ITGB1B.1
    Cell-Cell communication FBLIM1; DSCAML1; F11R.2; TESK1; CLDN3; PARVB; CDH4; CD151; KIRREL2; KIRRELB

    CDH2 has several biochemical functions, for example, alpha-catenin binding, beta-catenin binding, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDH2 itself. We selected most functions CDH2 had, and list some proteins which have the same functions with CDH2. You can find most of the proteins on our site.

    Function Related Protein
    alpha-catenin binding CDH2; JUP; JUB; NUMB; VCL; JUPA; AJUBA; CDH24; CTNNB1; PKP2
    beta-catenin binding C; PTPRK; SOX9; AXIN2; MED12; APC2; DVL3; CBY1; SMAD7; CARM1
    calcium ion binding SYTL4; FBN2; PCDHGC3; FBLN7; DNASE1L3; DHH; TTYH1; NOL3; PCDHGA1; GSNB
    gamma-catenin binding CTNNA1; PTBP3; APC; PTPRK; LEF1; FER; CDH1; DSG1; APC2; TCF7L2
    nitric-oxide synthase binding CAMK2D; CALM1; SLC6A4; DMD; SCN5A; SNTA1; CALM2; CAV1; CAV3; NOS1AP
    protein binding AKR1A1; COPG; CANX; STAP2; SETDB2; DNMBP; KLHL20; RGP1; GTPBP4; TNS4
    protein complex binding INS2; FLCN; ANKRD54; EPHB1; PDCL; IGBP1; ARRB2; PEX26; RIPK1; TXN2
    protein kinase binding PDGFRB; SREBF1; SFN; IKBKB; NEFH; MEF2A; BAD; GCET2; TNIP2; CADPS
    protein phosphatase binding IRS2; PARD3; CDC27; GNB2L1; ERBB2; JAK3; CTNNB1; VCP; PIK3R2; ANAPC7

    CDH2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDH2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDH2.


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