|Official Full Name||chymotrypsin-like elastase family, member 3A|
|Background||Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3A has little elastolytic activity. Like most of the human elastases, elastase 3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3A preferentially cleaves proteins after alanine residues. Elastase 3A may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1.|
|Synonyms||CELA3A; chymotrypsin-like elastase family, member 3A; ELA3; ELA3A; chymotrypsin-like elastase family member 3A; elastase 1; protease E; elastase-3A; elastase IIIA; OTTHUMP00000002835; elastase 3A, pancreatic|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CELA3A involved in several pathways and played different roles in them. We selected most pathways CELA3A participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with CELA3A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Pancreatic secretion||PLA2G12A; Car2; CLCA2; RAP1A; PLA2G2F; FXYD2; PRSS2; Slc4a2; RAB27B; ATP2B4|
|Protein digestion and absorption||DPP4; COL6A6; COL6A5; PGA5; MME; COL18A1; ATP1A4; SLC8A1; PRSS3; CPB2|
CELA3A has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by CELA3A itself. We selected most functions CELA3A had, and list some proteins which have the same functions with CELA3A. You can find most of the proteins on our site.
|serine-type endopeptidase activity||PCSK2; MMP2; PRSS28; EGFBP2; PCSK7; ST14A; PRSS8; RHBDD1; KLK1B16; TMPRSS7|
CELA3A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CELA3A here. Most of them are supplied by our site. Hope this information will be useful for your research of CELA3A.