Recombinant Human CELA3A Protein, GST-tagged

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Recombinant Human CELA3A Protein, GST-tagged

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Cat.No. : CELA3A-3224H
Product Overview : Human ELA3A full-length ORF ( AAH07028, 16 a.a. - 270 a.a.) recombinant protein with GST-tag at N-terminal.
Description : Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3A has little elastolytic activity. Like most of the human elastases, elastase 3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3A preferentially cleaves proteins after alanine residues. Elastase 3A may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 53.79 kDa
AA Sequence : SGYGPPSSHS SSRVVHGEDA VPYSWPWQVS LQYEKSGSFY HTCGGSLIAP DWVVTAGHCI SRDLTYQVVL GEYNLAVKEG PEQVIPINSE ELFVHPLWNR SCVACGNDIA LIKLSRSAQL GDAVQLASLP PAGDILPNKT PCYITGWGRL YTNGPLPDKL QQARLPVVDY KHCSRWNWWG STVKKTMVCA GGYIRSGCNG DSGGPLNCPT EDGGWQVHGV TSFVSGFGCN FIWKPTVFTR VSAFIDWIEE TIASH
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : CELA3A chymotrypsin like elastase family member 3A [ Homo sapiens (human) ]
Official Symbol : CELA3A
Synonyms : CELA3A; chymotrypsin like elastase family member 3A; Chymotrypsin Like Elastase Family Member 3A; Protease E; Elastase 3A, Pancreatic; Elastase IIIA; Elastase-3A; ELA3A; ELA3; Chymotrypsin-Like Elastase Family, Member 3A; Chymotrypsin-Like Elastase Family Member 3A; Elastase 3A, Pancreatic (Protease E); EC 3.4.21.70; Elastase 1; EC 3.4.21; chymotrypsin-like elastase family member 3A; elastase 1; elastase 3A, pancreatic; elastase IIIA; elastase-3A; protease E
Gene ID : 10136
mRNA Refseq : NM_005747
Protein Refseq : NP_005738
UniProt ID : P09093

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