CHD4 Protein, chromodomain helicase DNA binding protein 4


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Official Full Name chromodomain helicase DNA binding protein 4
Background Chromodomain-helicase-DNA-binding domain (CHD) proteins have been identified in a variety of organisms. This family of nine proteins is divided into three separate subfamilies: subfamily I (CHD1 and CHD2), subfamily II (CHD3 and CHD4), and subfamily III (
Synonyms CHD4; chromodomain helicase DNA binding protein 4; chromodomain-helicase-DNA-binding protein 4; Mi 2b; Mi2 BETA; CHD-4; ATP-dependent helicase CHD4; Mi-2 autoantigen 218 kDa protein; Mi-2b; Mi2-BETA; DKFZp686E06161
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CHD4-1180H Recombinant Human CHD4 Protein (1-239 aa), His-tagged E.coli His
    Human CHD4-2434H Recombinant Human CHD4 protein, His-tagged Insect Cell His
    Human CHD4-27065TH Recombinant Human CHD4 Wheat Germ N/A
    Human CHD4-2793H Recombinant Human CHD4 protein, GST-tagged Wheat Germ GST
    Human CHD4-346HCL Recombinant Human CHD4 cell lysate N/A
    Mouse CHD4-3379M Recombinant Mouse CHD4 Protein Mammalian Cell His

    CHD4 involved in several pathways and played different roles in them. We selected most pathways CHD4 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHD4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chromatin modifying enzymes SMYD2A; NCOA2; KAT8; SMARCD1; C3orf75; KANSL2; SUZ12; ACTL6A; SAP18; MSL3
    Chromatin organization ARID4A; SAP30; MTA3; MBD3B; PHF17; TADA1; KDM3A; SETD3; KDM3B; KDM5A
    Gene Expression NRBF2; GATAD2AB; ZKSCAN5; TSNAX; RNPS1; FARSB; MTF2; ZNF133; ZNF383; COX5B
    HDACs deacetylate histones MTA3; GATAD2A; BRMS1; SAP30; ARID4A; SUDS3; SAP30L; CHD4; GATAD2AB; MTA1
    RNA Polymerase I Promoter Clearance MBD3; GATAD2A; UBTF; MBD3A; RRN3; GATAD2B; MBD3B; GATAD2AB; MTA1; EFCAB11
    RNA Polymerase I Transcription MTA3; TAF1C; GATAD2A; CHD4A; CD3EAP; RRN3; EFCAB11; CBX3; PTRFB; CBX3A
    RNA Polymerase I Transcription Initiation GATAD2AB; MTA1; GATAD2A; GATAD2B; RRN3; MBD3A; CHD4A; MBD3B; MTA3; MTA2
    RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription MTA3; GATAD2B; PTRF; MTA1; SNAPC1A; GATAD2A; POLR3GLA; SNAPC1; MBD3A; PTRFB

    CHD4 has several biochemical functions, for example, ATP binding, ATP-dependent DNA helicase activity, DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHD4 itself. We selected most functions CHD4 had, and list some proteins which have the same functions with CHD4. You can find most of the proteins on our site.

    Function Related Protein
    ATP-dependent DNA helicase activity ERCC3; XRCC5; DDX11; WRN; CHST13; G3BP1; FBXO18; RECQL; DDX3X; CHD1
    contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding SMARCE1; HDAC1; MTA2; ACTB; CHD4; MBD3; GATAD2B; HDAC2; ACTL6A; SMARCC2
    contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding SMARCC2; ACTB; SMARCC1; RBBP4; ACTL6A; MTA2; SMARCA4; HDAC2; HDAC1; SMARCE1
    RNA polymerase II repressing transcription factor binding TBX5A; RBBP8; TCERG1; BBS5; GSC; RBPJ; PPARA; MIXL1; BBS10; TBP
    microtubule binding MAP1LC3B; MTUS2; KIFC1; FGF13; SPAST; GAS2L3; PAFAH1B1A; DPYSL2B; VAPA; GABARAPL2
    contributes_to nucleosomal DNA binding HDAC2; ACTL6A; CHD4; GATAD2B; SMARCC1; SMARCB1; MTA2; HDAC1; SMARCA4; SMARCE1
    protein binding COQ7; FRMPD2; ZFPM2; TNFRSF11A; NAGK; TCEB3B; PSMA4; ABT1; DTD2; WDR11
    zinc ion binding PHF2; KDM5C; DTNBB; APEX2; ADAM15; CCNB1IP1; TRIM39; ADAM32; POLR2I; CPA2

    CHD4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHD4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHD4.

    HDAC1; E7; HDAC2; MYC; MTA2; MBD3; RNF8; NR4A1; TAF9; USP36

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