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Recombinant Human CHD4 Protein (1-239 aa), His-tagged

Cat.No. : CHD4-1180H
Product Overview : Recombinant Human CHD4 Protein (1-239 aa) is produced by E. coli expression system. This protein is fused with a 6xHis tag at the N-terminal and C-terminal. Research Area: Epigenetics and Nuclear Signaling. Protein Description: Partial.
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Description : Component of the histone deacetylase NuRD complex which participates in the rodeling of chromatin by deacetylating histones.
Source : E. coli
Species : Human
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 31.8 Kda
Protein length : 1-239 aa
AA Sequence : MASGLGSPSPCSAGSEEEDMDALLN NSLPPPHPENEEDPEEDLSETETPK LKKKKKPKKPRDPKIPKSKRQKKER MLLCRQLGDSSGEGPEFVEEEEEVA LRSDSEGSDYTPGKKKKKKLGPKKE KKSKSKRKEEEEEEDDDDDSKEPKS SAQLLEDWGMEDIDHVFSEEDYRTL TNYKAFSQFVRPLIAAKNPKIAVSK MMMVLGAKWREFSTNNPFKGSSGAS VAAAAAAAVAVVES
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Gene Name : CHD4 chromodomain helicase DNA binding protein 4 [ Homo sapiens ]
Official Symbol : CHD4
Synonyms : CHD4; Mi 2b; Mi2 BETA; CHD-4; Mi-2b; Mi2-BETA; DKFZp686E06161;
Gene ID : 1108
mRNA Refseq : NM_001273
Protein Refseq : NP_001264
MIM : 603277
UniProt ID : Q14839

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does CHD4 interact with other components of the chromatin remodeling complex? 01/09/2022

CHD4 collaborates with the NuRD complex in chromatin remodeling.

What role does CHD4 play in gene regulation? 08/16/2021

CHD4 regulates gene transcription via chromatin accessibility.

What is the primary role of CHD4 in chromatin remodeling? 07/29/2020

CHD4 alters chromatin structure, aiding in DNA accessibility.

How do genetic variations in CHD4 affect gene expression? 05/11/2020

Genetic changes in CHD4 affect gene expression and cellular function.

What is the impact of altered CHD4 activity on cancer development? 09/12/2019

Altered CHD4 activity is associated with cancer progression.

How does CHD4 contribute to DNA damage repair? 05/05/2017

It remodels chromatin for efficient DNA repair.

What potential therapeutic applications arise from targeting CHD4 in cancer treatment? 03/29/2017

Targeting CHD4 offers potential cancer treatment strategies by affecting cell growth.

Customer Reviews (3)

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12/10/2022

    Efficient and precise, a cornerstone of our research.

    02/27/2022

      Dependable partner, trusted for data accuracy.

      10/22/2020

        Key to our research success, supports research consistency.

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