chmp1b
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  • Official Full Name
  • charged multivesicular body protein 1B
  • Background
  • CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are;components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of;surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and;cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and;regulation of cell cycle progression (Tsang et al., 2006 (PubMed 16730941)).
  • Synonyms
  • CHMP1B; charged multivesicular body protein 1B; chromatin modifying protein 1B; C18orf2; CHMP1.5; Vps46B; 2810405I11Rik; CHM1B_HUMAN; Chromatin-modifying protein 1b; hVps46-2; Vacuolar protein sorting-associated protein 46-2; Vps46-2; vacuolar protein sorting 46-2; C10orf2; C18-ORF2
Cat.#:CHMP1B-1247HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CHMP1B Protein, GST-Tagged
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Cat.#:CHMP1B-11183HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CHMP1B, GST-tagged
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Cat.#:CHMP1B-6794HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Charged Multivesicular Body Protein 1B, His-tagged
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Cat.#:CHMP1B-3404MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CHMP1B Protein
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Cat.#:CHMP1B-848RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CHMP1B Protein, His-tagged
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Cat.#:CHMP1B-1570CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CHMP1B
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Cat.#:CHMP1B-10373ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CHMP1B
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Cat.#:CHMP1B-7533HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CHMP1B 293 Cell Lysate
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Involved Pathway

CHMP1B involved in several pathways and played different roles in them. We selected most pathways CHMP1B participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHMP1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Endocytosis
VPS4A; CHMP2A; ACAP1; GRK1B; RAB11BA; RAB5B; ARRB2; CYTH3; RAB7A; EHD2B

Protein Function

CHMP1B has several biochemical functions, for example, protein binding, protein domain specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHMP1B itself. We selected most functions CHMP1B had, and list some proteins which have the same functions with CHMP1B. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein RAB14; MALL; TALDO1; PIP; ELK1; SMYD1; GIMAP5; PCDH18B; TNFAIP1; PDZK1
Function protein domain specific binding
Related Protein MECP2; AKAP1; IRS2; HIST2H4; YWHAE; ARFIP2; CHMP1B; FOXH1; HIST1H4J; CENPJ

Interacting Protein

CHMP1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHMP1B here. Most of them are supplied by our site. Hope this information will be useful for your research of CHMP1B.
STAMBP; USP8; USP54; PA; yerA; folC; secA2; q8cl86_yerpe; pi3p