chst11
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  • Official Full Name
  • carbohydrate (chondroitin 4) sulfotransferase 11
  • Background
  • The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • CHST11; carbohydrate (chondroitin 4) sulfotransferase 11; carbohydrate sulfotransferase 11; C4ST; C4St 1; C4ST1; HSA269537; C4S-1; C4ST-1; Chondroitin 4 O sulfotransferase 1; Chondroitin 4 sulfotransferase; Chondroitin 4-O-sulfotransferase 1; Chondroitin 4-sulfotransferase 1; CHST 11; CHSTB_HUMAN; IgH/CHST11 fusion; OTTHUMP00000242139; OTTHUMP00000242140
Cat.#:CHST11-1295HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CHST11 Protein, GST-Tagged
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Cat.#:CHST11-11224HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CHST11, His-tagged
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Cat.#:CHST11-148HTag:Fc
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CHST11, His tagged
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Cat.#:CHST11-1405RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CHST11 Protein
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Cat.#:CHST11-867RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CHST11 Protein, His-tagged
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Cat.#:CHST11-12090ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CHST11
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Cat.#:CHST11-001HCLTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CHST11 cell lysate
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Involved Pathway

CHST11 involved in several pathways and played different roles in them. We selected most pathways CHST11 participated on our site, such as Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHST11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
CHST12A; CHSY3; B3GAT3; CHPF2; CHST3; CSGALNACT1; CHST11; CSGALNACT2; CHSY1; CHST14

Protein Function

CHST11 has several biochemical functions, for example, N-acetylgalactosamine 4-O-sulfotransferase activity, N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity, chondroitin 4-sulfotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHST11 itself. We selected most functions CHST11 had, and list some proteins which have the same functions with CHST11. You can find most of the proteins on our site.
Function
Related Protein
Function N-acetylgalactosamine 4-O-sulfotransferase activity
Related Protein SULT3ST4; HS6ST3B; Chst5; SULT3ST3; CHST2A; SULT1D1; SULT1ST3; SULT1ST2; CHST8; SULT1ST8
Function N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity
Related Protein CHST15; CHST11
Function chondroitin 4-sulfotransferase activity
Related Protein CHST11; CHST12