|Official Full Name||claudin 4|
|Background||This gene encodes an integral membrane protein, which belongs to the claudin family. The protein is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.|
|Synonyms||CLDN4; claudin 4; CPETR, CPETR1; claudin-4; Clostridium perfringens enterotoxin receptor 1; CPE R; hCPE R; WBSCR8; Williams Beuren syndrome chromosomal region 8 protein; CPE-receptor; Williams-Beuren syndrome chromosomal region 8 protein; CPER; CPE-R; CPE|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CLDN4 involved in several pathways and played different roles in them. We selected most pathways CLDN4 participated on our site, such as Cell adhesion molecules (CAMs), Cell junction organization, Cell-Cell communication, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLDN4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cell adhesion molecules (CAMs)||LRRC4B; PVRL1B; HLA-DQA2; GLYCAM1; VCAM1; HLA-DRB4; CLDN15; ITGB7; ITGB1B.2; CD6|
|Cell junction organization||PVRL1A; F11R.2; CLDN20; CADM2A; CDH6; PARVB; CLDN16; CDH12A; FERMT2; CDH10A|
|Cell-Cell communication||F11R.2; NPHS1; CDH7; SKAP2; INADL; CLDN20; CADM2; DCC; LIMS1; CDH9|
|Cell-cell junction organization||CADM2A; CDH12; CDH4; INADL; JUPA; PVRL1A; CDH12A; CLDN16; CDH3; CDH5|
|Hepatitis C||IKBKB; BAD; CLDN15; CLDN23; IFN-a; CLDN4; PIK3CB; CLDN18; IFNA4; PPP2R1A|
|Leukocyte transendothelial migration||GNAI2; CLDN20; CLDN15; RAP1B; NCF1; ITGAL; ACTB; VASP; CLDN16; ITGAM|
|Tight junction||CLDN14; HRASA; SHROOM2; CLDNB; SMYHC1; ACTB; MYH1A; MYH9A; EPB41; SRC|
|Tight junction interactions||CLDN20; CLDN16; CLDN4; INADL; CLDN7; CLDN3; CLDN23|
CLDN4 has several biochemical functions, for example, identical protein binding, structural molecule activity, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLDN4 itself. We selected most functions CLDN4 had, and list some proteins which have the same functions with CLDN4. You can find most of the proteins on our site.
|identical protein binding||HJURP; RYR2; ACPP; MRI1; SNRNP200; IIGP1; RIPK3; AIM2; IRF3; POLG2|
|structural molecule activity||CLDND; NGS; DESMB; KRT4; ANK1; SPRR2D; OC90; KRTT1C19E; EPB41L3B; CLDN16|
|transmembrane signaling receptor activity||KLRF1; FZD9B; HIST2H3C2; PTH1RA; KIR2DL4; CLEC2H; TLR2-2; TRPV1; SIGLEC8; TLR5|
CLDN4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLDN4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLDN4.