CLIC2

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CLIC2

Official Full Name chloride intracellular channel 2
Background Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 2 is a member of the p64 family; the protein is detected in fetal liver and adult skeletal muscle tissue.This gene maps to the candidate region on chromosome X for incontinentia pigmenti.
Synonyms CLIC2; chloride intracellular channel 2; chloride intracellular channel protein 2; XAP121; CLIC 2b; CLIC2_HUMAN; CLIC2b; OTTHUMP00000196471; XAP 121; OTTHUMP00000024248
    • Species :
    • Chicken
    • Human
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CLIC2-3907H Recombinant Human CLIC2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CLIC2-1478H Recombinant Human CLIC2 Protein, GST-tagged Wheat Germ GST
    Human CLIC2-27815TH Recombinant Human CLIC2, His-tagged E.coli His
    Human CLIC2-27817TH Recombinant Human CLIC2 N/A
    Human CLIC2-3512H Recombinant Human Chloride Intracellular Channel 2, His-tagged E.coli His
    Human CLIC2-7447HCL Recombinant Human CLIC2 293 Cell Lysate HEK293 N/A
    Rat CLIC2-1449R Recombinant Rat CLIC2 Protein Mammalian Cell His
    Rhesus Macaque CLIC2-909R Recombinant Rhesus monkey CLIC2 Protein, His-tagged Mammalian Cell His
    Chicken CLIC2-2786C Recombinant Chicken CLIC2 Mammalian Cell His
    Zebrafish CLIC2-682Z Recombinant Zebrafish CLIC2 Mammalian Cell His

    CLIC2 involved in several pathways and played different roles in them. We selected most pathways CLIC2 participated on our site, such as Ion channel transport, Stimuli-sensing channels, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLIC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ion channel transport ATP2B3A; OSTM1; ATP1A1A.3; TRPM1B; TRPM1A; PDZD11; TRPM6; Ano3; ATP2C2; TRPC4
    Stimuli-sensing channels ANO9; MCOLN3; WNK2; UNC79; SCNN1D; ASIC1A; SLC9B2; SLC9A10; TRPC5A; BEST1
    Transmembrane transport of small molecules SLC6A5; TTYH3; SLC2A13; SLC13A4; CLCN2; ABCG4B; SLC24A6; ABCD3B; SLC24A5; CUTC

    CLIC2 has several biochemical functions, for example, chloride channel activity, glutathione peroxidase activity, NOT glutathione transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLIC2 itself. We selected most functions CLIC2 had, and list some proteins which have the same functions with CLIC2. You can find most of the proteins on our site.

    Function Related Protein
    chloride channel activity SLC26A3.1; SLC26A2; CLCN4; CLCA1; SLC26A4; FXYD3; GABRA5; ANO2; CLCA5; CLIC1
    glutathione peroxidase activity PRDX6; GPX4B; GPX8; GRX2; GPX1; GPX6; CLIC2; GSTK1; GSTZ1; GPX7
    NOT glutathione transferase activity CLIC2; CLIC5; ALOX5AP; CLIC3; CLIC1
    protein binding GLRA1; CD48; ADPRH; RBP7; DES; OLA1; SCOC; BAZ1A; VAV1; ZNF124
    voltage-gated ion channel activity CLCN3; CLIC2; KCNS3A; KCNJ1A.5; SCN8AA; CLIC5B; CACNG8A; KCNK4; KCNK16; KCNIP3

    CLIC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLIC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLIC2.

    FN1

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