cthrc1
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  • Official Full Name
  • collagen triple helix repeat containing 1
  • Background
  • This locus encodes a protein that may play a role in the cellular response to arterial injury through involvement in vascular remodeling. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]
  • Synonyms
  • CTHRC1; collagen triple helix repeat containing 1; collagen triple helix repeat-containing protein 1;
Cat.#:CTHRC1-3360HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CTHRC1 Protein, MYC/DDK-tagged
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Cat.#:CTHRC1-5241HTag:MBP/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CTHRC1 Protein, MBP/His-tagged
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Cat.#:CTHRC1-5254HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CTHRC1 Protein, His-tagged
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Cat.#:CTHRC1-28025THTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CTHRC1 protein, GST-tagged
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Cat.#:CTHRC1-3047HTag:MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Collagen Triple Helix Repeat Containing 1
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Cat.#:CTHRC1-3225HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CTHRC1, His tagged
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Cat.#:Cthrc1-28MTag:FLAG®
Source (Host):CHOSpecies:Mouse
Product nameRecombinant Mouse Cthrc1 protein, FLAG®-tagged
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Cat.#:CTHRC1-4024MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CTHRC1 Protein
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Cat.#:Cthrc1-1134RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Cthrc1 Protein, His-tagged
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Cat.#:CTHRC1-1656RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CTHRC1 Protein
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Cat.#:CTHRC1-2448HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CTHRC1 cell lysate
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Involved Pathway

CTHRC1 involved in several pathways and played different roles in them. We selected most pathways CTHRC1 participated on our site, such as Noncanonical Wnt signaling pathway, Wnt signaling network, which may be useful for your reference. Also, other proteins which involved in the same pathway with CTHRC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Noncanonical Wnt signaling pathway
CHD7; CTHRC1; ROR2
Wnt signaling network
WIF1; CTHRC1; ATP6AP2; IGFBP4; RSPO1; RYK

Protein Function

CTHRC1 has several biochemical functions, for example, Wnt-protein binding, frizzled binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CTHRC1 itself. We selected most functions CTHRC1 had, and list some proteins which have the same functions with CTHRC1. You can find most of the proteins on our site.
Function
Related Protein
Function Wnt-protein binding
Related Protein PTPRO; APCDD1; FZD1; ROR1; FZD9; Fzd4; LRP5L; ROR2; FRZB; SFRP2
Function frizzled binding
Related Protein WNT2BA; DVL1; CTHRC1; BAMBI; WNT6; DVL1B; SDCBP; NDP; WNT4B; WNT5B

Interacting Protein

CTHRC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTHRC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CTHRC1.
ZDHHC17; TFAP2C

CTHRC1 Related Articles

Duarte, CW; Stohn, JP; et al. Elevated Plasma Levels of the Pituitary Hormone Cthrc1 in Individuals with Red Hair but Not in Patients with Solid Tumors. PLOS ONE 9:-(2014).
Ma, MZ; Zhuang, C; et al. CTHRC1 Acts as a Prognostic Factor and Promotes Invasiveness of Gastrointestinal Stromal Tumors by Activating Wnt/PCP-Rho Signaling. NEOPLASIA 16:-(2014).