• Official Full Name
  • dipeptidyl-peptidase 6
  • Background
  • This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Variations in this gene may be associated with susceptibility to amyotrophic lateral sclerosis and with idiopathic ventricular fibrillation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
  • Synonyms
  • DPP6; dipeptidyl-peptidase 6; VF2; DPPX; dipeptidyl aminopeptidase-like protein 6; DPP VI; dipeptidylpeptidase 6; dipeptidyl peptidase VI; dipeptidyl peptidase IV-related protein; dipeptidyl aminopeptidase IV-related protein;
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat DPP6 protein, His-tagged
Source (Host):YeastSpecies:Rat
Product nameRecombinant Rat DPP6 protein, His-tagged
Source (Host):HEK293Species:Human
Product nameRecombinant Human DPP6 Protein Variant 1
Source (Host):HEK293Species:Human
Product nameRecombinant Human DPP6 Protein, MYC/DDK-tagged
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DPP6 Protein, GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DPP6 protein, His & T7-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DPP6, His-tagged
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat DPP6 Protein

Protein Function

DPP6 has several biochemical functions, for example, NOT dipeptidyl-peptidase activity, potassium channel regulator activity, serine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DPP6 itself. We selected most functions DPP6 had, and list some proteins which have the same functions with DPP6. You can find most of the proteins on our site.
Related Protein
Function NOT dipeptidyl-peptidase activity
Related Protein DPP10; DPP6
Function potassium channel regulator activity
Related Protein SGK3; SGK2B; KCNE1L; KCNMB2; SUMO1; ARPP19; SGK1; PIAS3; LRRC26; DPP10
Function serine-type peptidase activity
Related Protein HTRA3; DPP10; PLAUA; TMPRSS11F; KLK15; PRSS8; TMPRSS11B; KLK10; Gzmg; PRSS59.2

Interacting Protein

DPP6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DPP6 here. Most of them are supplied by our site. Hope this information will be useful for your research of DPP6.