ECHS1
-
Official Full Name
enoyl CoA hydratase, short chain, 1, mitochondrial
-
Overview
The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. -
Synonyms
ECHS1; enoyl CoA hydratase, short chain, 1, mitochondrial; enoyl Coenzyme A hydratase, short chain, 1, mitochondrial; enoyl-CoA hydratase, mitochondrial; SCEH; C80529; EC 4.2.1.17; ECHS 1; Enoyl CoA hydratase 1; Enoyl CoA hydratase mitochondrial; Enoyl CoA hydratase short chain 1 mitochondrial; Enoyl Coenzyme A hydratase short chain 1; Enoyl Coenzyme A hydratase short chain 1 mitochondrial; Mitochondrial short chain enoyl coenzyme A hydratase 1; OTTHUMP00000020811; Short chain enoyl CoA hydratase; enoyl-CoA hydratase 1; short-chain enoyl-CoA hydratase;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- HA
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- ECHS1 Related Articles
ECHS1 involved in several pathways and played different roles in them. We selected most pathways ECHS1 participated on our site, such as Beta oxidation of butanoyl-CoA to acetyl-CoA, Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA, Beta oxidation of hexanoyl-CoA to butanoyl-CoA, which may be useful for your reference. Also, other proteins which involved in the same pathway with ECHS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Beta oxidation of butanoyl-CoA to acetyl-CoA | |
| Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA | |
| Beta oxidation of hexanoyl-CoA to butanoyl-CoA | |
| Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA | |
| Beta oxidation of octanoyl-CoA to hexanoyl-CoA | |
| Biosynthesis of antibiotics | pykF;PAICS;DAO;CYP51A1;CTH;ECHS1;AMDHD2;DLD;AK7 |
| Butanoate metabolism | ACAT1;BDH1;OXCT1A;GAD1B;OXCT2B;AACS;EHHADH;ALDH5A1;HADH |
| Carbon metabolism | ESD;PRPS2;GOT2;ALDOC;GOT2A;TKTL1;PGAM1;PRPS1;TALDO1 |
ECHS1 has several biochemical functions, for example, enoyl-CoA hydratase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ECHS1 itself. We selected most functions ECHS1 had, and list some proteins which have the same functions with ECHS1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| enoyl-CoA hydratase activity | HADHAA;ECHS1;HADHAB;HADHB;AUH;EHHADH;HADHA |
| protein binding | SMURF2;RCAN3;DLGAP4;BDKRB1;RCN2;CCDC103;CDKL3;ANG;ARF6 |
ECHS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ECHS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ECHS1.
LRRK2; Stat3; STAT3; LRRK1; RIPK2; EIF1B; GH1; EPB41; TIMP2; TFE3; MCC; HLA-B; VHL; GABARAPL2; YWHAZ
- Q&As
- Reviews
Ask a Question for All ECHS1 Products
Required fields are marked with *
My Review for All ECHS1 Products
Required fields are marked with *
