ERAP1

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ERAP1

Official Full Name endoplasmic reticulum aminopeptidase 1
Background ARTS1/Adipocyte-derived leucine aminopeptidase (A-LAP) is a member of the M1 family of zinc metallopeptidases. A-LAP is upregulatable by gamma interferon and trims N-terminal lysine, leucine, tyrosine and asparagines residues when they are not followed by
Synonyms ERAP1; endoplasmic reticulum aminopeptidase 1; A LAP; adipocyte derived leucine aminopeptidase; aminopeptidase regulator of TNFR1 shedding; ARTS 1; ERAAP1; KIAA0525; PILS AP; puromycin insensitive leucyl specific aminopeptidase; aminopeptidase PILS; adipo
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse ERAP1-2101M Recombinant Mouse ERAP1 Protein (731-930 aa), His-Myc-tagged E.coli His/Myc
    Human ARTS-1-873H Recombinant Human ARTS-1 protein, GST-tagged Wheat Germ GST
    Human ERAP1-2119H Recombinant Human ERAP1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human ERAP1-532H Recombinant Human ERAP1 Protein, His-tagged NS0 His
    Mouse ERAP1-5276M Recombinant Mouse ERAP1 Protein Mammalian Cell His
    Rat ERAP1-2132R Recombinant Rat ERAP1 Protein Mammalian Cell His

    ERAP1 involved in several pathways and played different roles in them. We selected most pathways ERAP1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with ERAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System KLRB1A; SIGLEC6; IGKV1-5; TRAF7; SIGLEC9; ICAM4; CXADR; LILRB3; KLRG1; CTSL2
    Antigen Presentation: Folding, assembly and peptide loading of class I MHC SEC24A; B2ML; SEC23A; ERAP2; ERAP1
    Class I MHC mediated antigen processing &amp WSB1; UBR1; UBE2V2; ERAP2; LTN1; STUB1; UBE2E3; WWP1; ASB18; TPP2
    presentation PJA2; LRR1; TRIM39; ASB8; ERAP2; NPEPPS; SPSB4; TRAF7; SEC24A; RNF111
    Immune System LILRB2; ASB3; OASL; TRIM38; DYNC1I2; KLRB1A; LILRB1; MB21D1; DEFB4A; PELI1

    ERAP1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by ERAP1 itself. We selected most functions ERAP1 had, and list some proteins which have the same functions with ERAP1. You can find most of the proteins on our site.

    Function Related Protein
    aminopeptidase activity NPEPPS; XPNPEP2; NPEPL1; CTSH; XPNPEP3; ERAP2; TPP2; PEPD; XPNPEP1; RNPEP
    interleukin-1, Type II receptor binding ERAP1; IL1RN
    interleukin-6 receptor binding PYCARD; IL6; ERAP1; CNTF; ADAM17
    metalloaminopeptidase activity ENPEP; ANPEP; ERAP1; RNPEP; Npepo; RNPEPL1; METAP2B; LTA4H; XPNPEP1; ANPEPA
    metalloexopeptidase activity NPEPL1; ERAP1; NUDT16; DPEP3; DPEP1; METAP2B; METAP2; DPEP2; RNPEP; METAP1D
    peptide binding NPFFR1L2; PLOD1; HCRTR2; Npepo; OXTR; RPS6KB2; RPS6KB1; CLTB; GPR22; AVPR2L
    protein binding SNX2; DARS; F11R; FZR1; MTMR14; RCC2; C11orf57; MITD1; DUSP2; NOMO2
    tumor necrosis factor receptor binding TRAF4; TNFSF13B; TNFSF15; FADD; Fasl; ERAP1; TRAF3; TRAP1; FASLG; TNFSF13
    zinc ion binding RNF182; CPO; GLI2; PPARAA; CPXM2; RYBPA; PHF17; KIAA0913; SNCA; FTR43

    ERAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ERAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ERAP1.

    IL6R; TNFRSF1A; yapH; 1-phosphatidyl-1d-myo-inositol 3,4,5-trisphosphate

    Smith, JA; et al. Update on Ankylosing Spondylitis: Current Concepts in Pathogenesis. CURRENT ALLERGY AND ASTHMA REPORTS 15:-(2015).
    Carmona, FD; Martin, J; et al. Genetics of vasculitis. CURRENT OPINION IN RHEUMATOLOGY 27:10-17(2015).

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