FPR1
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Official Full Name
formyl peptide receptor 1
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Overview
This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation. -
Synonyms
FPR1; formyl peptide receptor 1; fMet-Leu-Phe receptor; FMLP; FPR; fMet Leu Phe receptor; FMLP Receptor; FMLPR; FPR 1; FPR receptor; FPR1_HUMAN; N formyl peptide chemoattractant receptor; N formyl peptide receptor; N formylpeptide chemoattractant receptor; N-formyl peptide receptor; N-formylpeptide chemoattractant receptor;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Assay Kits
- Gorilla gorilla gorilla (Western lowland gorilla)
- Homo sapiens (Human)
- Human
- Macaca mulatta (Rhesus macaque)
- Mouse
- Mus musculus (Mouse)
- Pan troglodytes (Chimpanzee)
- Pongo pygmaeus (Bornean orangutan)
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- Flag|His
- GST
- His
- His (Fc)
- Avi
- His|GST|Myc
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- FPR1 Related Articles
- FPR1 Related Gene Family
- FPR1 Related Research Area
FPR1 involved in several pathways and played different roles in them. We selected most pathways FPR1 participated on our site, such as Rap signaling pathway, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with FPR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Rap signaling pathway | MLLT4;MAGI1;ANGPT4;P2RY1;MET;PFN3;ITGB2;TEK;IGF1R |
| Neuroactive ligand-receptor interaction | HTR6;EDNRB2;CALCRLA;CHRNB3A;CCKAR;AVPR2;P2RY6;GABRA3;PRL |
| Staphylococcus aureus infection | HLA-DPA1;C5;ICAM1;HLA-DRB5;C4A;DSG1A;PTAFR;DSG1;FCGR3 |
FPR1 has several biochemical functions, for example, N-formyl peptide receptor activity, RAGE receptor binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FPR1 itself. We selected most functions FPR1 had, and list some proteins which have the same functions with FPR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| N-formyl peptide receptor activity | FPR-RS4;FPR1;FPR2;FPR-RS6;FPR-RS3 |
| RAGE receptor binding | S100A8;HMGB1;S100A12;S100A7;S100A4;FPR1;HMGB2;S100B;S100A9 |
| protein binding | HIST4H4;GAP43;DUSP14;CDC5L;MT1F;VPS4B;RPL12;LARS;CABLES1 |
| receptor activity | GRIA4A;ITGB3A;ANPEP;F2RL1.2;CD200R4;GPA33;NOTCH1B;NLGN1;MED14 |
FPR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FPR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FPR1.
MAPK13; ADRBK1; MAPK3; lcrD
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