gdf11
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  • Official Full Name
  • growth differentiation factor 11
  • Background
  • The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.
  • Synonyms
  • GDF11; growth differentiation factor 11; growth/differentiation factor 11; BMP 11; GDF-11; bone morphogenetic protein 11; BMP11; BMP-11
Cat.#:GDF11-280HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GDF11 Protein, His-tagged
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Cat.#:GDF11-4820HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GDF11 Protein, GST-tagged
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Cat.#:Gdf11-282MTag:
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Gdf11 Protein, His-tagged
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Cat.#:Gdf11-283RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Gdf11 Protein, His-tagged
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Cat.#:GDF11-01HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GDF11 protein
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Cat.#:GDF11-1078HTag:Met
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GDF11
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Cat.#:GDF11-38HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GDF11, His-tagged
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Cat.#:GDF11-1079MTag:Met
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse GDF11
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Cat.#:Gdf11-108MTag:
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Gdf11 protein
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Cat.#:GDF11-6284MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GDF11 Protein
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Cat.#:Gdf11-1080RTag:
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Gdf11 protein
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Cat.#:GDF11-12223ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GDF11
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Cat.#:GDF11-242Tag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Growth Differentiation Factor 11
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Cat.#:GDF11-137HGTag:
Source (Host):E. coliSpecies:Human
Product nameGMP Recombinant Human GDF11 Protein
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Protein Function

GDF11 has several biochemical functions, for example, cytokine activity, growth factor activity, transforming growth factor beta receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GDF11 itself. We selected most functions GDF11 had, and list some proteins which have the same functions with GDF11. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein TGFB3; IL6; Kitl; LEFTY1; TNFSF10; BMP7; IL24; Ccl27a; GPI; TNFSF14
Function growth factor activity
Related Protein AMBN; IL9; MSTNB; NGF; FIGF; LIF; IL11; GPI; FGF11A; FGF18
Function transforming growth factor beta receptor binding
Related Protein GDF15; MSTNB; GDF7; BMP4; GDF11; SMAD2; INHBAB; GDF10B; BMP7A; GDF6

Interacting Protein

GDF11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GDF11 here. Most of them are supplied by our site. Hope this information will be useful for your research of GDF11.
ACVR2B; Acvr1b; Tgfbr1; Acvr1c; WFIKKN2; WFIKKN1

GDF11 Related Gene Family

TGF