|Official Full Name||hydroxyacid oxidase (glycolate oxidase) 1|
|Background||This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.|
|Synonyms||HAO1; hydroxyacid oxidase (glycolate oxidase) 1; GOX1; hydroxyacid oxidase 1; GOX; (S) 2 hydroxy acid oxidase; Glycolate oxidase; HAOX1; HAOX1_HUMAN; MGC142225; MGC142227; OTTHUMP00000030231; (S)-2-hydroxy-acid oxidase|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
HAO1 involved in several pathways and played different roles in them. We selected most pathways HAO1 participated on our site, such as Glyoxylate and dicarboxylate metabolism, Metabolic pathways, Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with HAO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Glyoxylate and dicarboxylate metabolism||CS; PCCA; AGXTA; ACAT1; ACO1; AGXT; GLULA; DLDH; MDH1AA; SHMT2|
|Metabolic pathways||HOGA1; UROS; KCNG4; NDUFA1; SDHD; ATP6V1G2; PGAM2; RPN1; QDPRB2; ATP6V1H|
|Carbon metabolism||SUCLG2; IDH3G; PKMA; PGP; PDHA1; SDHDA; OGDHL; AGXTA; PGD; PRPS1B|
|Peroxisome||ACSL4; NOS2; GNPAT; BAAT; HACL1; EPHX2; PEX11B; SOD1; PIPOX; MPV17L|
HAO1 has several biochemical functions, for example, (S)-2-hydroxy-acid oxidase activity, FMN binding, glycolate oxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HAO1 itself. We selected most functions HAO1 had, and list some proteins which have the same functions with HAO1. You can find most of the proteins on our site.
|(S)-2-hydroxy-acid oxidase activity||HAO1; HAO2|
|FMN binding||TYW1B; MTRR; DHODH; PNPO; NOS2; CREG2; POR; NOS2B; NOS2A; NOS3|
|glycolate oxidase activity||HAO1|
|glyoxylate oxidase activity||HAO1|
|long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity||HAO2; HAO1|
|medium-chain-(S)-2-hydroxy-acid oxidase activity||HAO1; HAO2|
|receptor binding||KCNA5; RND1; Icosl; NTF7; FGF6A; RCHY1; TIGIT; RARA; PVRL3; CLCF1|
|very-long-chain-(S)-2-hydroxy-acid oxidase activity||HAO1; HAO2|
HAO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HAO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HAO1.