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HMBS

  • Official Full Name

    hydroxymethylbilane synthase

  • Overview

    This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
  • Synonyms

    HMBS; hydroxymethylbilane synthase; PBGD, PORC, porphobilinogen deaminase , porphyria, acute; Chester type , UPS, uroporphyrinogen I synthase; porphobilinogen deaminase; HEM3_HUMAN; PBG D; PBG-D; PBGD; Pre uroporphyrinogen synthase; Pre-uroporphyrinogen synthase; UPS; Uroporphyrinogen I synthase; Uroporphyrinogen I synthetase; OTTHUMP00000238530; OTTHUMP00000238532; OTTHUMP00000238533; OTTHUMP00000238534; OTTHUMP00000238537; OTTHUMP00000238539; OTTHUMP00000238540; OTTHUMP00000238541; OTTHUMP00000238580; PORC; EC 2.5.1.61;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Others
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HMBS-13835H Recombinant Human HMBS, GST-tagged E.coli GST 1-361a.a.
Human HMBS-4856H Recombinant Human HMBS Protein, GST-tagged Wheat Germ GST
Human HMBS-1929H Recombinant Human Hydroxymethylbilane Synthase, His-tagged His
Human HMBS-29326TH Recombinant Human HMBS Wheat Germ N/A 361 amino acids
Human HMBS-39H Recombinant Human HMBS protein, His-tagged HEK293 His
Human HMBS-5483HCL Recombinant Human HMBS 293 Cell Lysate HEK293 N/A
Human HMBS-5484HCL Recombinant Human HMBS 293 Cell Lysate HEK293 N/A
Human HMBS-2031H Recombinant Human HMBS Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HMBS-1374HFL Recombinant Full Length Human HMBS Protein, C-Flag-tagged Mammalian cells Flag
Human HMBS-3636HF Recombinant Full Length Human HMBS Protein, GST-tagged In Vitro Cell Free System GST 361 amino acids
Human HMBS-6081H Recombinant Human HMBS Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HMBS-1078H-B Recombinant Human HMBS Protein Pre-coupled Magnetic Beads HEK293
Human HMBS-2354H Recombinant Human HMBS Protein (Ser2-His361), C-His tagged Mammalian cells C-His Ser2-His361
Human HMBS-1078H Recombinant Human HMBS Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human HMBS-3347H Recombinant Human HMBS protein, His-tagged E.coli His 1-361 aa
Human HMBS-2355H Recombinant Human HMBS Protein (Leu85-Ser337), N-His tagged E.coli N-His Leu85-Ser337
Human HMBS-237HF Recombinant Full Length Human HMBS Protein In Vitro Cell Free System 361 amino acids
Mouse Hmbs-1133M Recombinant Mouse Hmbs Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rhesus Macaque HMBS-2105R Recombinant Rhesus monkey HMBS Protein, His-tagged Mammalian Cell His
Rhesus Macaque HMBS-1926R Recombinant Rhesus Macaque HMBS Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque HMBS-1926R-B Recombinant Rhesus Macaque HMBS Protein Pre-coupled Magnetic Beads HEK293
CBCRY24 Porphobilinogen deaminase E.coli N/A
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