Recombinant Full Length Human HMBS Protein, C-Flag-tagged
Cat.No. : | HMBS-1374HFL |
Product Overview : | Recombinant Full Length Human HMBS Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 39.1 kDa |
AA Sequence : | MSGNGNAAATAEENSPKMRVIRVGT RKSQLARIQTDSVVATLKASYPGLQ FEIIAMSTTGDKILDTALSK IGEKSLFTKELEHALEKNEVDLVVH SLKDLPTVLPPGFTIGAICKRENPH DAVVFHPKFVGKTLETLPEK SVVGTSSLRRAAQLQRKFPHLEFRS IRGNLNTRLRKLDEQQEFSAIILAT AGLQRMGWHNRVGQILHPEE CMYAVGQGALGVEVRAKDQDILDLV GVLHDPETLLRCIAERAFLRHLEGG CSVPVAVHTAMKDGQLYLTG GVWSLDGSDSIQETMQATIHVPAQH EDGPEDDPQLVGITARNIPRGPQLA AQNLGISLANLLLSKGAKNI LDVARQLNDAHTRTRPLEQKLISEE DLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Metabolic pathways, Porphyrin and chlorophyll metabolism |
Gene Name : | HMBS hydroxymethylbilane synthase [ Homo sapiens (human) ] |
Official Symbol : | HMBS |
Synonyms : | UPS; PBGD; PORC; PBG-D |
Gene ID : | 3145 |
mRNA Refseq : | NM_000190.4 |
Protein Refseq : | NP_000181.2 |
MIM : | 609806 |
UniProt ID : | P08397 |
Products Types
◆ Recombinant Protein | ||
HMBS-4856H | Recombinant Human HMBS Protein, GST-tagged | +Inquiry |
Hmbs-1133M | Recombinant Mouse Hmbs Protein, MYC/DDK-tagged | +Inquiry |
HMBS-1078H | Recombinant Human HMBS Protein, His (Fc)-Avi-tagged | +Inquiry |
HMBS-1926R | Recombinant Rhesus Macaque HMBS Protein, His (Fc)-Avi-tagged | +Inquiry |
HMBS-2355H | Recombinant Human HMBS Protein (Leu85-Ser337), N-His tagged | +Inquiry |
◆ Lysates | ||
HMBS-5483HCL | Recombinant Human HMBS 293 Cell Lysate | +Inquiry |
HMBS-5484HCL | Recombinant Human HMBS 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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